Disease stratification in GCA and PMR: state of the art and future perspectives
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely related conditions
characterized by systemic inflammation, a predominant IL-6 signature, an excellent …
characterized by systemic inflammation, a predominant IL-6 signature, an excellent …
Systematic literature review of systemic corticosteroid use for asthma management
Systemic corticosteroid use to manage uncontrolled asthma and its associated healthcare
burden may account for important health-related adverse effects. We conducted a systematic …
burden may account for important health-related adverse effects. We conducted a systematic …
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …
cancers. While these immunotherapies have improved patient outcomes in many clinical …
Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis
Background Eosinophilic granulomatosis with polyangiitis is an eosinophilic vasculitis.
Mepolizumab, an anti–interleukin-5 monoclonal antibody, reduces blood eosinophil counts …
Mepolizumab, an anti–interleukin-5 monoclonal antibody, reduces blood eosinophil counts …
Adverse outcomes from initiation of systemic corticosteroids for asthma: long-term observational study
DB Price, F Trudo, J Voorham, X Xu… - Journal of asthma …, 2018 - Taylor & Francis
Purpose Prior work suggests a threshold of four courses/year of systemic corticosteroid
(SCS) therapy is associated with adverse consequences. The objective of this study was to …
(SCS) therapy is associated with adverse consequences. The objective of this study was to …
Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study
Objective To determine the frequency of prescriptions for short term use of oral
corticosteroids, and adverse events (sepsis, venous thromboembolism, fractures) associated …
corticosteroids, and adverse events (sepsis, venous thromboembolism, fractures) associated …
[HTML][HTML] Long-term systemic corticosteroid exposure: a systematic literature review
Purpose While corticosteroids are relatively inexpensive and commonly used as treatment
for a variety of conditions, long-term use is known to be associated with certain toxicities …
for a variety of conditions, long-term use is known to be associated with certain toxicities …
Clinical practice guideline: hoarseness (dysphonia)(update)
RJ Stachler, DO Francis, SR Schwartz… - … –Head and Neck …, 2018 - journals.sagepub.com
Objective This guideline provides evidence-based recommendations on treating patients
who present with dysphonia, which is characterized by altered vocal quality, pitch, loudness …
who present with dysphonia, which is characterized by altered vocal quality, pitch, loudness …
Oral corticosteroid exposure and adverse effects in asthmatic patients
Background Significant adverse effects (AEs) have been associated with continuous
exposure to oral corticosteroids (OCSs). The potential association with intermittent exposure …
exposure to oral corticosteroids (OCSs). The potential association with intermittent exposure …
Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British …
Objective To determine the prevalence of systemic corticosteroid-induced morbidity in
severe asthma. Design Cross-sectional observational study. Setting The primary care …
severe asthma. Design Cross-sectional observational study. Setting The primary care …