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Supervised learning with decision tree-based methods in computational and systems biology
At the intersection between artificial intelligence and statistics, supervised learning allows
algorithms to automatically build predictive models from just observations of a system …
algorithms to automatically build predictive models from just observations of a system …
A review on the development of bacterial multi-epitope recombinant protein vaccines via reverse vaccinology
Y Li, MHR Farhan, X Yang, Y Guo, Y Sui, J Chu… - International Journal of …, 2024 - Elsevier
Bacterial vaccines play a crucial role in combating bacterial infectious diseases. Apart from
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …
Biological Systems Discovery In Silico: Radical S-Adenosylmethionine Protein Families and Their Target Peptides for Posttranslational Modification
Data mining methods in bioinformatics and comparative genomics commonly rely on
working definitions of protein families from prior computation. Partial phylogenetic profiling …
working definitions of protein families from prior computation. Partial phylogenetic profiling …
Metals in protein structures: a review of their principal features
MM Harding, MW Nowicki… - Crystallography …, 2010 - Taylor & Francis
Metals are present in more than one-third of all proteins as they occur in nature, and are
usually important in biological function or maintenance of the structure. Some are present as …
usually important in biological function or maintenance of the structure. Some are present as …
Diversity, structure and regulation of microbial metallothionein: metal resistance and possible applications in sequestration of toxic metals
Metallothioneins (MTs) are a group of cysteine-rich, universal, low molecular weight proteins
distributed widely in almost all major taxonomic groups ranging from tiny microbes to highly …
distributed widely in almost all major taxonomic groups ranging from tiny microbes to highly …
Designing of a multi-epitopes based vaccine against Haemophilius parainfluenzae and its validation through integrated computational approaches
Haemophilus parainfluenzae is a Gram-negative opportunist pathogen within the mucus of
the nose and mouth without significant symptoms and has an ability to cause various …
the nose and mouth without significant symptoms and has an ability to cause various …
Bioinformatical approaches to characterize intrinsically disordered/unstructured proteins
Intrinsically disordered/unstructured proteins exist without a stable three-dimensional (3D)
structure as highly flexible conformational ensembles. The available genome sequences …
structure as highly flexible conformational ensembles. The available genome sequences …
The rough guide to in silico function prediction, or how to use sequence and structure information to predict protein function
Choosing the right function prediction tools. The vast majority of known proteins have not yet
been characterized experimentally, and there is very little that is known about their function …
been characterized experimentally, and there is very little that is known about their function …
Metalloproteomics: forward and reverse approaches in metalloprotein structural and functional characterization
About one-third of all proteins are associated with a metal. Metalloproteomics is defined as
the structural and functional characterization of metalloproteins on a genome-wide scale …
the structural and functional characterization of metalloproteins on a genome-wide scale …
mebipred: identifying metal-binding potential in protein sequence
Motivation metal-binding proteins have a central role in maintaining life processes. Nearly
one-third of known protein structures contain metal ions that are used for a variety of needs …
one-third of known protein structures contain metal ions that are used for a variety of needs …