Domperidone is a highly water insoluble drug exhibiting poor dissolution pattern. The
purpose of this work was to increase the dissolution rate of Domperidone by formation of …

This study was carried out to improve the dissolution properties of loratadine by solid
dispersion technique. A series of solid dispersions of loratadine in PVP K-30 (1: 1, 1: 3 and …

Context: Supercritical fluid methods offer an alternative to conventional mixing methods,
particularly for heat sensitive drugs and where an organic solvent is undesirable. Objective …

This work describes a melt granulation technique to improve the solubility and dissolution
characteristics of a poorly water-soluble drug, rifapentine. Melt granulation technique is a …

Glimepiride is a member of the third generation of sulfonylureas used to treat diabetes
mellitus. Even though glimepiride has moderate water solubility, its slow rate of dissolution …

Solubility enhancement of poorly aqueous soluble drugs is an important aspect of
formulation development. The objective of the study was to compare the aqueous solubility …

The solubility behavior of drugs is one of the most challenging aspects in formulation
development. Most of the newly invented or naturally occurring phytochemical entities are …

Therapeutic effectiveness of a drug depends upon the bioavailability and ultimately upon the
solubility of drug molecules. Solubility is one of the important parameter to achieve desired …

In fact, it has been estimated that 40% of new chemical entities currently being discovered
are poorly watersoluble. Unfortunately, many of these potential drugs area bandoned in the …

The recognizable proof of ordinary and carcinogenic stem cell and the latest developments
made in seclusion and principles of stem cells have quickly picked up consideration in the …