Prevalence and incidence of Huntington's disease: an updated systematic review and meta‐analysis

A Medina, Y Mahjoub, L Shaver… - Movement …, 2022 - Wiley Online Library
The incidence and prevalence of Huntington's disease (HD) based on a systematic review
and meta‐analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per …

Focusing the pivotal role of nanotechnology in Huntington's disease: an insight into the recent advancements

S Singh, Hema, N Sharma, M Sachdeva, T Behl… - … Science and Pollution …, 2022 - Springer
Neurodegeneration is the loss of neuronal capacity and structure over time which causes
neurodegenerative disorders like Alzheimer, amyotrophic lateral sclerosis, Parkinson, and …

[HTML][HTML] Huntington's disease drug development: a phase 3 pipeline analysis

HJ Van de Roovaart, N Nguyen, TD Veenstra - Pharmaceuticals, 2023 - mdpi.com
Huntington's Disease (HD) is a severely debilitating neurodegenerative disorder in which
sufferers exhibit different combinations of movement disorders, dementia, and behavioral or …

[HTML][HTML] The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells

A Ramadan, A Mohammed, AA Elnour, A Sadeq… - Saudi Pharmaceutical …, 2023 - Elsevier
Background Huntington's disease is an inherited progressive neurodegenerative disorder
caused by an expansion of the polyglutamine tract leading to malformation and aggregation …

Chaperone-dependent mechanisms as a pharmacological target for neuroprotection

MV Voronin, EV Abramova, ER Verbovaya… - International Journal of …, 2023 - mdpi.com
Modern pharmacotherapy of neurodegenerative diseases is predominantly symptomatic
and does not allow vicious circles causing disease development to break. Protein misfolding …

[HTML][HTML] Economic burden of huntington's disease in China: results from a national-wide cross-sectional study

S Chen, H Zhang, J Yu, X Cao, S Zhang, D Dong - Neuroepidemiology, 2024 - karger.com
Background: Huntington's disease (HD) poses a significant socio-economic burden globally.
Existing research on HD's economic burden predominantly comes from Western settings …

Epidemiology of Huntington's Disease in Latin America: A Systematic Review and Meta‐Analysis

A Medina Escobar, T Pringsheim… - Movement …, 2024 - Wiley Online Library
Abstract Background Latin America has played a crucial role in advancing our
understanding of Huntington's disease (HD). However, previous global reviews include …

Economic burden of Huntington's disease: A systematic review

P Gokhale, L Villa Zapata - Journal of Huntington's Disease, 2025 - journals.sagepub.com
Background Huntington's disease (HD) is an autosomal dominant neurodegenerative
disease, characterized by progressive motor, cognitive, and psychiatric symptoms. The …

Comorbidities and clinical outcomes in adult-and juvenile-onset Huntington's disease: a study of linked Swedish National Registries (2002–2019)

H Furby, S Moore, AL Nordstroem, R Houghton… - Journal of …, 2023 - Springer
Background Huntington's disease (HD) is a rare, neurodegenerative disease and its
complex motor, cognitive and psychiatric symptoms exert a lifelong clinical burden on both …

Basal insulin initiation in adults with type 2 diabetes mellitus: A retrospective cohort study using administrative health data in Alberta, Canada

P Senior, J Hahn, G Mau, P Manivong… - Canadian Journal of …, 2024 - Elsevier
Objectives Pharmacologic treatment of type 2 diabetes mellitus (T2DM) follows a stepwise
approach. Typically, metformin monotherapy is first-line treatment, followed by other …