Biomaterial implantation into the human body plays a key role in the medical field and
biological applications. Increasing the life expectancy of biomaterial implants, reducing the …

Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

An appropriate cell microenvironment is key to tissue engineering and regenerative
medicine. Revealing the factors that influence the cell microenvironment is a fundamental …

Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

Cell–material interactions constitute a key fundamental topic in biomaterials study. Various
cell cues and matrix cues as well as soluble factors regulate cell behaviors on materials …

There is currently an unmet need for the supply of autologous, patient-specific stem cells for
regenerative therapies in the clinic. Mesenchymal stem cell differentiation can be driven by …

Polydimethylsiloxane (PDMS) has been extensively exploited to study stem cell physiology
in the field of mechanobiology and microfluidic chips due to their transparency, low cost and …

One of the greatest trends currently revolutionizing healthcare is the introduction of
advanced additive manufacturing techniques, also known as 3D printing, for personalized …

One of the recent paradigm shifts in stem cell biology has been the discovery that stem cells
can begin to differentiate into mature tissue cells when exposed to intrinsic properties of the …