Long COVID science, research and policy
Long COVID represents the constellation of post-acute and long-term health effects caused
by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every …
by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every …
Long COVID: Clinical characteristics, proposed pathogenesis and potential therapeutic targets
G Kenny, L Townsend, S Savinelli… - Frontiers in Molecular …, 2023 - frontiersin.org
The emergence of persistent ill-health in the aftermath of SARS-CoV-2 infection has
presented significant challenges to patients, healthcare workers and researchers. Termed …
presented significant challenges to patients, healthcare workers and researchers. Termed …
Remodeling of T cell dynamics during long COVID is dependent on severity of SARS-CoV-2 infection
M Wiech, P Chroscicki, J Swatler, D Stepnik… - Frontiers in …, 2022 - frontiersin.org
Several COVID-19 convalescents suffer from the post-acute COVID-syndrome (PACS)/long
COVID, with symptoms that include fatigue, dyspnea, pulmonary fibrosis, cognitive …
COVID, with symptoms that include fatigue, dyspnea, pulmonary fibrosis, cognitive …
Clinical, radiological and pathological findings in patients with persistent lung disease following SARS-CoV-2 infection
Some patients experience pulmonary sequelae after SARS-CoV-2 infection, ranging from
self-limited abnormalities to major lung diseases. Morphological analysis of lung tissue may …
self-limited abnormalities to major lung diseases. Morphological analysis of lung tissue may …
Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets
X Liu, W **ong, M Ye, T Lu, K Yuan, S Chang… - … and Targeted Therapy, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been looming globally for
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …
Mild to moderate post-COVID-19 alters markers of lymphocyte activation, exhaustion, and immunometabolic responses that can be partially associated by physical …
Aim This study aimed to evaluate if physical activity is associated with systemic and cellular
immunometabolic responses, in young adults after mild-to-moderate COVID-19 infection …
immunometabolic responses, in young adults after mild-to-moderate COVID-19 infection …
PD-L1: from cancer immunotherapy to therapeutic implications in multiple disorders
D Lee, M Cho, E Kim, Y Seo, JH Cha - Molecular Therapy, 2024 - cell.com
The PD-L1/PD-1 signaling pathway is the gold standard for cancer immunotherapy.
Therapeutic antibodies targeting PD-1, such as nivolumab (Opdivo) and pembrolizumab …
Therapeutic antibodies targeting PD-1, such as nivolumab (Opdivo) and pembrolizumab …
[HTML][HTML] Exhaustion and over-activation of immune cells in COVID-19: Challenges and therapeutic opportunities
Exhaustion of immune cells in COVID-19 remains a serious concern for infection
management and therapeutic interventions. As reported, immune cells such as T effector …
management and therapeutic interventions. As reported, immune cells such as T effector …
Long COVID: clinical framing, biomarkers, and therapeutic approaches
More than two years after the onset of the COVID-19 pandemic, healthcare providers are
facing an emergency within an emergency, the so-called long COVID or post-COVID-19 …
facing an emergency within an emergency, the so-called long COVID or post-COVID-19 …
[HTML][HTML] The therapeutic potential of PD-1/PD-L1 pathway on immune-related diseases: based on the innate and adaptive immune components
P Zhang, Y Wang, Q Miao, Y Chen - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Currently, immunotherapy targeting programmed cell death 1 (PD-1) or programmed death
ligand 1 (PD-L1) has revolutionized the treatment strategy of human cancer patients …
ligand 1 (PD-L1) has revolutionized the treatment strategy of human cancer patients …