Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the
second most lethal human cancer. A portion of patients with advanced HCC can significantly …

microRNA-23a (miR-23a) is one of the most extensively studied miRNAs in different types of
human cancer, and plays various roles in the initiation, progression, and treatment of tumors …

Background Drug resistance to sorafenib greatly limited the benefits of treatment in patients
with hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) participate in the development …

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Intense
efforts have been made to elucidate the pathogeny, but the molecular mechanisms of HCC …

Background Hepatocellular carcinoma (HCC) is one of the most intractable tumors in the
world due to its high rate of recurrence and heterogeneity. Liver cancer initiating cells also …

RESULTS Enforced expression of the miR-23 cluster in T cells leads to spontaneous
lymphohyperactivation phenotypes To determine the role of the miR-23 clusters in T cell …

Hepatocellular carcinoma (HCC) has been one of the most highly lethal cancers. The
acquisition of drug resistance accounts for the majority of poor effects of chemotherapy in …

Background Growing evidence indicates that miR-200c is involved in carcinogenesis and
tumor progression in non-small-cell lung cancer (NSCLC). However, its precise biological …

Introduction Altered epigenetic map is frequently observed in cancer and recent
investigations have demonstrated a pertinent role of epigenetic modifications in the …

Current literature provided information that alteration in microRNA expression impacted
sensitivity or resistance of certain tumor types to anticancer treatment, including the possible …