Genome-resolved metagenomics: a game changer for microbiome medicine
N Kim, J Ma, W Kim, J Kim, P Belenky… - Experimental & Molecular …, 2024 - nature.com
Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …
rise to a new domain in biomedical research: microbiome medicine. This emerging field …
<? mode longmeta?> SPIRE: a Searchable, Planetary-scale mIcrobiome REsource
Meta'omic data on microbial diversity and function accrue exponentially in public
repositories, but derived information is often siloed according to data type, study or sampled …
repositories, but derived information is often siloed according to data type, study or sampled …
Generation of accurate, expandable phylogenomic trees with uDance
Phylogenetic trees provide a framework for organizing evolutionary histories across the tree
of life and aid downstream comparative analyses such as metagenomic identification …
of life and aid downstream comparative analyses such as metagenomic identification …
Challenges in computational discovery of bioactive peptides in'omics data
Peptides have a plethora of activities in biological systems that can potentially be exploited
biotechnologically. Several peptides are used clinically, as well as in industry and …
biotechnologically. Several peptides are used clinically, as well as in industry and …
The mOTUs online database provides web-accessible genomic context to taxonomic profiling of microbial communities
Determining the taxonomic composition (taxonomic profiling) is a fundamental task in
studying environmental and host-associated microbial communities. However, genome …
studying environmental and host-associated microbial communities. However, genome …
Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal E. coli in the murine gut
Resource competition is a driver of gut microbiota composition. Bacteria can outcompete
metabolically similar rivals through the limitation of shared growth-fuelling nutrients. The …
metabolically similar rivals through the limitation of shared growth-fuelling nutrients. The …
A fast comparative genome browser for diverse bacteria and archaea
Genome sequencing has revealed an incredible diversity of bacteria and archaea, but there
are no fast and convenient tools for browsing across these genomes. It is cumbersome to …
are no fast and convenient tools for browsing across these genomes. It is cumbersome to …
BGCFlow: systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets
Genome mining is revolutionizing natural products discovery efforts. The rapid increase in
available genomes demands comprehensive computational platforms to effectively extract …
available genomes demands comprehensive computational platforms to effectively extract …
Getting your money's worth: Testing the value of data for hydrological model calibration
Despite the big data era, observational data continue to be a limiting factor in the
environmental sciences. To collect the most informative field data, studies on the value of …
environmental sciences. To collect the most informative field data, studies on the value of …
Calcium‐Dependent Lipopeptide Antibiotics against Drug‐Resistant Pathogens Discovered via Host‐Dependent Heterologous Expression of a Cloned Biosynthetic …
Historically, small molecules biosynthesised by bacteria have been an excellent source for
antibacterial drugs. Today, however, the rediscovery of known compounds is a significant …
antibacterial drugs. Today, however, the rediscovery of known compounds is a significant …