[PDF][PDF] Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host

W Khovidhunkit, MS Kim, RA Memon… - The Journal of …, 2004 - pdfs.semanticscholar.org
Infection and inflammation induce the acutephase response (APR), leading to multiple
alterations in lipid and lipoprotein metabolism. Plasma triglyceride levels increase from …

Peroxisome proliferator‐activated receptor targets for the treatment of metabolic diseases

FA Monsalve, RD Pyarasani… - Mediators of …, 2013 - Wiley Online Library
Metabolic syndrome is estimated to affect more than one in five adults, and its prevalence is
growing in the adult and pediatric populations. The most widely recognized metabolic risk …

Up-regulation of PPAR-γ mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c induction

P Pettinelli, LA Videla - The Journal of Clinical Endocrinology & …, 2011 - academic.oup.com
Introduction: Triglyceride accumulation in the liver is an early feature in the development of
nonalcoholic fatty liver disease (NAFLD) associated with human obesity, which is a …

PPARγ as a new therapeutic target in inflammatory bowel diseases

L Dubuquoy, C Rousseaux, X Thuru, L Peyrin-Biroulet… - Gut, 2006 - gut.bmj.com
The peroxisome proliferator activated receptor γ (PPARγ) is a nuclear receptor highly
expressed in the colon and playing a key role in bacterial induced inflammation. Regulation …

PPARγ AND GLUCOSE HOMEOSTASIS

F Picard, J Auwerx - Annual review of nutrition, 2002 - annualreviews.org
▪ Abstract Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor
involved in the control of metabolism. Research on PPARγ is oriented towards …

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130

Q Wang, YC Li, J Wang, J Kong, Y Qi… - Proceedings of the …, 2008 - National Acad Sciences
Adipogenesis involves cell proliferation and differentiation, both of which have been shown
to be regulated by micro (mi) RNA. During mouse preadipocyte 3T3L1 cell differentiation, we …

Collagen–hyaluronic acid scaffolds for adipose tissue engineering

N Davidenko, JJ Campbell, ES Thian, CJ Watson… - Acta biomaterialia, 2010 - Elsevier
Three-dimensional (3-D) in vitro models of the mammary gland require a scaffold matrix that
supports the development of adipose stroma within a robust freely permeable matrix. 3-D …

Intermuscular and intramuscular adipose tissues: Bad vs. good adipose tissues

GJ Hausman, U Basu, M Du, M Fernyhough-Culver… - Adipocyte, 2014 - Taylor & Francis
Human studies of the influence of aging and other factors on intermuscular fat (INTMF) were
reviewed. Intermuscular fat increased with weight loss, weight gain, or with no weight …

Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy

SM Grundy - Nature reviews Drug discovery, 2006 - nature.com
The metabolic syndrome—a collection of factors associated with increased risk for
cardiovascular disease and diabetes—is becoming increasingly common, largely as a result …

15d-PGJ2: the anti-inflammatory prostaglandin?

JU Scher, MH Pillinger - Clinical immunology, 2005 - Elsevier
15-Deoxy-Δ-12, 14-prostaglandin J2 (15d-PGJ2) is the most recently discovered
prostaglandin. This cyclopentanone, the dehydration end product of PGD2, differs from other …