Autophagy is a highly conserved catabolic process cells use to maintain their homeostasis
by degrading misfolded, damaged and excessive proteins, nonfunctional organelles, foreign …

Over the past two decades, the molecular machinery that underlies autophagic responses
has been characterized with ever increasing precision in multiple model organisms …

The removal of misfolded, ubiquitinated proteins is an essential part of the protein quality
control. The ubiquitin‐proteasome system (UPS) and autophagy are two interconnected …

Autophagosomes are unique organelles that form de novo as double-membrane vesicles
engulfing cytosolic material for destruction. Their biogenesis involves membrane …

Clearance of biomolecular condensates by selective autophagy is thought to play a crucial
role in cellular homeostasis. However, the mechanism underlying selective autophagy of …

Selective autophagy is a conserved homeostatic pathway that involves engulfment of
specific cargo molecules into specialized organelles called autophagosomes. The ubiquitin …

Bifidobacteria are early colonizers of the human gut and play central roles in human health
and metabolism. To thrive in this competitive niche, these bacteria evolved the capacity to …

Proteins are known to perform an astonishing array of functions thanks to their ability to
cooperate and modulate each other's properties. Inside cells, proteins can assemble into …

In selective autophagy, cargo selectivity is determined by autophagy receptors. However, it
remains scarcely understood how autophagy receptors recognize specific protein cargos. In …

Autophagy, a conserved cellular process in eukaryotes, has evolved to a sophisticated
process to dispose of intracellular constituents and plays important roles in plant …