[HTML][HTML] Mechanisms of selective autophagy

G Zaffagnini, S Martens - Journal of molecular biology, 2016 - Elsevier
Selective autophagy contributes to intracellular homeostasis by mediating the degradation
of cytoplasmic material such as aggregated proteins, damaged or over-abundant …

[HTML][HTML] Autophagosome maturation and fusion

F Reggiori, C Ungermann - Journal of molecular biology, 2017 - Elsevier
Macroautophagy, or simply autophagy, is a degradative pathway that delivers cytoplasmic
components, including cytosol and organelles, to the lysosome in double-membrane …

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

W B'chir, AC Maurin, V Carraro, J Averous… - Nucleic acids …, 2013 - academic.oup.com
In response to different environmental stresses, eIF2α phosphorylation represses global
translation coincident with preferential translation of ATF4, a master regulator controlling the …

Atg9 establishes Atg2-dependent contact sites between the endoplasmic reticulum and phagophores

R Gómez-Sánchez, J Rose, R Guimarães… - Journal of Cell …, 2018 - rupress.org
Autophagy is an evolutionarily conserved cellular transport pathway in which cytoplasmic
components including protein aggregates and damaged or superfluous organelles are …

Mechanism and functions of membrane binding by the Atg5–Atg12/Atg16 complex during autophagosome formation

J Romanov, M Walczak, I Ibiricu, S Schüchner… - The EMBO …, 2012 - embopress.org
Autophagy is a conserved process for the bulk degradation of cytoplasmic material.
Triggering of autophagy results in the formation of double membrane‐bound vesicles …

Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy

B Wurzer, G Zaffagnini, D Fracchiolla, E Turco, C Abert… - elife, 2015 - elifesciences.org
Autophagy is a major pathway for the clearance of harmful material from the cytoplasm.
During autophagy, cytoplasmic material is delivered into the lysosomal system by organelles …

p53-mediated molecular control of autophagy in tumor cells

M Mrakovcic, LF Fröhlich - Biomolecules, 2018 - mdpi.com
Autophagy is an indispensable mechanism of the eukaryotic cell, facilitating the removal and
renewal of cellular components and thereby balancing the cell's energy consumption and …

The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling

FX Guo, Q Wu, P Li, L Zheng, S Ye, XY Dai… - Cell Death & …, 2019 - nature.com
Atherosclerosis is a progressive, chronic inflammation in arterial walls. Long noncoding
RNAs (lncRNAs) participate in inflammation, but the exact mechanism in atherosclerosis is …

ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling

W Zheng, W **e, D Yin, R Luo, M Liu, F Guo - Cell Communication and …, 2019 - Springer
Background Autophagy and ER stress are involved in maintaining some well-orchestrated
mechanisms aimed at either restoring cellular homeostasis or performing cell death …

Clathrin and phosphatidylinositol-4, 5-bisphosphate regulate autophagic lysosome reformation

Y Rong, M Liu, L Ma, W Du, H Zhang, Y Tian, Z Cao… - Nature cell …, 2012 - nature.com
Autophagy is a lysosome-based degradation pathway. During autophagy, lysosomes fuse
with autophagosomes to form autolysosomes. Following starvation-induced autophagy …