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[HTML][HTML] Mechanisms of selective autophagy
Selective autophagy contributes to intracellular homeostasis by mediating the degradation
of cytoplasmic material such as aggregated proteins, damaged or over-abundant …
of cytoplasmic material such as aggregated proteins, damaged or over-abundant …
[HTML][HTML] Autophagosome maturation and fusion
F Reggiori, C Ungermann - Journal of molecular biology, 2017 - Elsevier
Macroautophagy, or simply autophagy, is a degradative pathway that delivers cytoplasmic
components, including cytosol and organelles, to the lysosome in double-membrane …
components, including cytosol and organelles, to the lysosome in double-membrane …
The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
W B'chir, AC Maurin, V Carraro, J Averous… - Nucleic acids …, 2013 - academic.oup.com
In response to different environmental stresses, eIF2α phosphorylation represses global
translation coincident with preferential translation of ATF4, a master regulator controlling the …
translation coincident with preferential translation of ATF4, a master regulator controlling the …
Atg9 establishes Atg2-dependent contact sites between the endoplasmic reticulum and phagophores
R Gómez-Sánchez, J Rose, R Guimarães… - Journal of Cell …, 2018 - rupress.org
Autophagy is an evolutionarily conserved cellular transport pathway in which cytoplasmic
components including protein aggregates and damaged or superfluous organelles are …
components including protein aggregates and damaged or superfluous organelles are …
Mechanism and functions of membrane binding by the Atg5–Atg12/Atg16 complex during autophagosome formation
J Romanov, M Walczak, I Ibiricu, S Schüchner… - The EMBO …, 2012 - embopress.org
Autophagy is a conserved process for the bulk degradation of cytoplasmic material.
Triggering of autophagy results in the formation of double membrane‐bound vesicles …
Triggering of autophagy results in the formation of double membrane‐bound vesicles …
Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy
Autophagy is a major pathway for the clearance of harmful material from the cytoplasm.
During autophagy, cytoplasmic material is delivered into the lysosomal system by organelles …
During autophagy, cytoplasmic material is delivered into the lysosomal system by organelles …
p53-mediated molecular control of autophagy in tumor cells
M Mrakovcic, LF Fröhlich - Biomolecules, 2018 - mdpi.com
Autophagy is an indispensable mechanism of the eukaryotic cell, facilitating the removal and
renewal of cellular components and thereby balancing the cell's energy consumption and …
renewal of cellular components and thereby balancing the cell's energy consumption and …
The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling
Atherosclerosis is a progressive, chronic inflammation in arterial walls. Long noncoding
RNAs (lncRNAs) participate in inflammation, but the exact mechanism in atherosclerosis is …
RNAs (lncRNAs) participate in inflammation, but the exact mechanism in atherosclerosis is …
ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling
W Zheng, W **e, D Yin, R Luo, M Liu, F Guo - Cell Communication and …, 2019 - Springer
Background Autophagy and ER stress are involved in maintaining some well-orchestrated
mechanisms aimed at either restoring cellular homeostasis or performing cell death …
mechanisms aimed at either restoring cellular homeostasis or performing cell death …
Clathrin and phosphatidylinositol-4, 5-bisphosphate regulate autophagic lysosome reformation
Autophagy is a lysosome-based degradation pathway. During autophagy, lysosomes fuse
with autophagosomes to form autolysosomes. Following starvation-induced autophagy …
with autophagosomes to form autolysosomes. Following starvation-induced autophagy …