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Towards a genomics-informed, real-time, global pathogen surveillance system
Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
[HTML][HTML] Next-generation sequencing technologies and their application to the study and control of bacterial infections
J Besser, HA Carleton, P Gerner-Smidt… - Clinical microbiology …, 2018 - Elsevier
Background With the efficiency and the decreasing cost of next-generation sequencing, the
technology is being rapidly introduced into clinical and public health laboratory practice …
technology is being rapidly introduced into clinical and public health laboratory practice …
VFDB 2019: a comparative pathogenomic platform with an interactive web interface
The virulence factor database (VFDB, http://www. mgc. ac. cn/VFs/) is devoted to providing
the scientific community with a comprehensive warehouse and online platform for …
the scientific community with a comprehensive warehouse and online platform for …
In Silico Genoty** of Escherichia coli Isolates for Extraintestinal Virulence Genes by Use of Whole-Genome Sequencing Data
AM Malberg Tetzschner, JR Johnson… - Journal of clinical …, 2020 - journals.asm.org
ABSTRACT Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause in
humans of urinary tract infection and bacteremia. The previously published web tool …
humans of urinary tract infection and bacteremia. The previously published web tool …
PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens
Background Antibiotic resistance is a major health problem, as drugs that were once highly
effective no longer cure bacterial infections. WGS has previously been shown to be an …
effective no longer cure bacterial infections. WGS has previously been shown to be an …
The use of next generation sequencing for improving food safety: Translation into practice
Abstract Next Generation Sequencing (NGS) combined with powerful bioinformatic
approaches are revolutionising food microbiology. Whole genome sequencing (WGS) of …
approaches are revolutionising food microbiology. Whole genome sequencing (WGS) of …
MicroScope: an integrated platform for the annotation and exploration of microbial gene functions through genomic, pangenomic and metabolic comparative analysis
Large-scale genome sequencing and the increasingly massive use of high-throughput
approaches produce a vast amount of new information that completely transforms our …
approaches produce a vast amount of new information that completely transforms our …
Whole-genome sequencing of bacterial pathogens: the future of nosocomial outbreak analysis
Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …
[HTML][HTML] Genomics for emerging pathogen identification and monitoring: Prospects and obstacles
Emerging infectious diseases (EIDs) pose an increasingly significant global burden, driven
by urbanization, population explosion, global travel, changes in human behavior, and …
by urbanization, population explosion, global travel, changes in human behavior, and …
Pathogenicity assessment of Shiga toxin‐producing Escherichia coli (STEC) and the public health risk posed by contamination of food with STEC
The provisional molecular approach, proposed by EFSA in 2013, for the pathogenicity
assessment of Shiga toxin‐producing Escherichia coli (STEC) has been reviewed. Analysis …
assessment of Shiga toxin‐producing Escherichia coli (STEC) has been reviewed. Analysis …