Practical guidance on the use of sacubitril/valsartan for heart failure

AJ Sauer, R Cole, BC Jensen, J Pal, N Sharma… - Heart failure …, 2019 - Springer
Sacubitril/valsartan is a first-in-class angiotensin receptor-neprilysin inhibitor (ARNI) that has
been recommended in clinical practice guidelines to reduce morbidity and mortality in …

[HTML][HTML] 2019 ACC expert consensus decision pathway on risk assessment, management, and clinical trajectory of patients hospitalized with heart failure: a report of …

SM Hollenberg, L Warner Stevenson, T Ahmad… - Journal of the American …, 2019 - jacc.org
The American College of Cardiology (ACC) has a long history of develo** documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

The role of angiotensin receptor–neprilysin inhibitors in cardiovascular disease—existing evidence, knowledge gaps, and future directions

AP Ambrosy, RJ Mentz, M Fiuzat… - European journal of …, 2018 - Wiley Online Library
Although traditional renin–angiotensin system antagonists including angiotensin‐converting
enzyme inhibitors and angiotensin receptor blockers have revolutionized the treatment of …

Comparison of the efficacy and safety of sacubitril/valsartan versus ramipril in patients with ST-segment elevation myocardial infarction

A Rezq, M Saad, M El Nozahi - The American journal of cardiology, 2021 - Elsevier
The role of sacubitril and/or valsartan in patient with heart failure (HF) is established.
Whether sacubitril and/or valsartan plays a role in improving outcomes in patients after ST …

Applicability of US Food and Drug Administration Labeling for Dapagliflozin to Patients With Heart Failure With Reduced Ejection Fraction in US Clinical Practice: The …

M Vaduganathan, SJ Greene, S Zhang… - JAMA …, 2021 - jamanetwork.com
Importance In May 2020, dapagliflozin was approved by the US Food and Drug
Administration (FDA) as the first sodium-glucose cotransporter 2 inhibitor for heart failure …

Patient eligibility for established and novel guideline-directed medical therapies after acute heart failure hospitalization

N Moghaddam, NM Hawkins, R McKelvie, S Poon… - Heart Failure, 2023 - jacc.org
Background Acute heart failure (AHF) hospitalization presents an opportunity to optimize
pharmacotherapy to improve outcomes. Objectives This study's aim was to define eligibility …

Sacubitril/valsartan eligibility and outcomes in the ESC‐EORP‐HFA Heart Failure Long‐Term Registry: bridging between European Medicines Agency/Food and Drug …

CJ Kapelios, M Lainscak, G Savarese… - European journal of …, 2019 - Wiley Online Library
Aims To assess the proportion of patients with heart failure and reduced ejection fraction
(HFrEF) who are eligible for sacubitril/valsartan (LCZ696) based on the European Medicines …

Guideline-directed medical therapy for the treatment of heart failure with reduced ejection fraction

J Patel, N Rassekh, GC Fonarow, P Deedwania… - Drugs, 2023 - Springer
Guideline-directed medical therapy (GDMT) is the cornerstone of pharmacological therapy
for patients with heart failure with reduced ejection fraction (HFrEF) and consists of the four …

Effects of sacubitril/valsartan on functional status and exercise capacity in real-world patients

CW Lau, P Martens, S Lambeets, M Dupont… - Acta …, 2019 - Taylor & Francis
Background: Sacubitril/valsartan significantly reduced heart failure (HF) hospitalisations and
mortality in the PARADIGM-HF-trial. However real-world data on symptomatic and functional …

Representativeness of a heart failure trial by race and sex: results from ASCEND-HF and GWTG-HF

SJ Greene, AD DeVore, S Sheng, GC Fonarow… - JACC: Heart Failure, 2019 - jacc.org
Objectives: This study sought to determine the degree to which US patients enrolled in a
heart failure (HF) trial represent patients in routine US clinical practice according to race and …