Achromobacter is a genus of nonfermenting Gram-negative bacteria under order
Burkholderiales. Although primarily isolated from respiratory tract of people with cystic …

Metallo-β-lactamases are resistance determinants of increasing clinical relevance in Gram-
negative bacteria. Because of their broad range, potent carbapenemase activity and …

In patients with cystic fibrosis (CF), the lung is a remarkable ecological niche in which the
microbiome is subjected to important selective pressures. An inexorable colonization by …

Bacteria belonging to the genus Achromobacter are widely distributed in natural
environments and have been recognized as emerging pathogens for their contribution to a …

Achromobacter xylosoxidans is an environmental opportunistic pathogen, which infects an
increasing number of immunocompromised patients. In this study we combined genomic …

Achromobacter xylosoxidans is an emerging pathogen in cystic fibrosis patients. The
multidrug resistance of these bacteria remains poorly understood. We have characterized in …

An Achromobacter xylosoxidans strain from the Tripoli central hospital produced a unique
metallo-β-lactamase, designated TMB-1, which is related to DIM-1 (62%) and GIM-1 (51%) …

Metallo-β-lactamases (MBLs) are a rapidly evolving group of β-lactamases, which hydrolyze
most β-lactams including the carbapenems. Of the known MBLs, VIMs are one of the most …

ABSTRACT A chromosomally encoded class D β-lactamase, OXA-114, was characterized
from Achromobacter xylosoxidans strain CIP69598. β-Lactamase OXA-114 shared 56 …

In recent years, advances in diagnosis and treatment have significantly modified the short-
and long-term prognosis of cystic fibrosis (CF) patients. However, as in the past, the most …