The contribution of homocysteine metabolism disruption to endothelial dysfunction: state-of-the-art
R Esse, M Barroso, I Tavares de Almeida… - International journal of …, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …
Causes of hyperhomocysteinemia and its pathological significance
J Kim, H Kim, H Roh, Y Kwon - Archives of pharmacal research, 2018 - Springer
In the last 10 years, homocysteine has been regarded as a marker of cardiovascular disease
and a definite risk factor for many other diseases. Homocysteine is biosynthesized from …
and a definite risk factor for many other diseases. Homocysteine is biosynthesized from …
[HTML][HTML] HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration
Z Tang, Y Ju, X Dai, N Ni, Y Liu, D Zhang, H Gao… - Redox biology, 2021 - Elsevier
Oxidative stress-mediated retinal pigment epithelium (RPE) degeneration plays a vital role
in retinal degeneration with irreversible visual impairment, most notably in age-related …
in retinal degeneration with irreversible visual impairment, most notably in age-related …
Hyperhomocysteinemia: clinical insights
F Al Mutairi - Journal of central nervous system disease, 2020 - journals.sagepub.com
Homocysteine (Hcy) is a sulfhydryl-containing amino acid, and intermediate metabolite
formed in metabolising methionine (Met) to cysteine (Cys); defective Met metabolism can …
formed in metabolising methionine (Met) to cysteine (Cys); defective Met metabolism can …
Homocysteine induces inflammation in retina and brain
Homocysteine (Hcy) is an amino acid that requires vitamins B12 and folic acid for its
metabolism. Vitamins B12 and folic acid deficiencies lead to hyperhomocysteinemia (HHcy …
metabolism. Vitamins B12 and folic acid deficiencies lead to hyperhomocysteinemia (HHcy …
Homocysteine and diabetes: Role in macrovascular and microvascular complications
Diabetes mellitus (DM) can lead to the development of macro-and microvascular
complications. Homocysteine (Hcy) may play a role in the development of cardiovascular …
complications. Homocysteine (Hcy) may play a role in the development of cardiovascular …
Nutritional and medical food therapies for diabetic retinopathy
Diabetic retinopathy (DR) is a form of microangiopathy. Reducing oxidative stress in the
mitochondria and cell membranes decreases ischemic injury and end-organ damage to the …
mitochondria and cell membranes decreases ischemic injury and end-organ damage to the …
Implication of hyperhomocysteinemia in blood retinal barrier (BRB) dysfunction
Elevated plasma homocysteine (Hcy) level, known as hyperhomocysteinemia (HHcy) has
been linked to different systemic and neurological diseases, well-known as a risk factor for …
been linked to different systemic and neurological diseases, well-known as a risk factor for …
Nuclear factor erythroid-2-related factor 2 signaling in the neuropathophysiology of inherited metabolic disorders
Inherited metabolic disorders (IMDs) are rare genetic conditions that affect multiple organs,
predominantly the central nervous system. Since treatment for a large number of IMDs is …
predominantly the central nervous system. Since treatment for a large number of IMDs is …
[HTML][HTML] Retinal Vein Occlusion–Background Knowledge and Foreground Knowledge Prospects—A Review
M Lendzioszek, A Bryl, E Poppe, K Zorena… - Journal of Clinical …, 2024 - mdpi.com
Thrombosis of retinal veins is one of the most common retinal vascular diseases that may
lead to vascular blindness. The latest epidemiological data leave no illusions that the …
lead to vascular blindness. The latest epidemiological data leave no illusions that the …