The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

Cancer immunotherapy is a major breakthrough in the history of tumor therapy in the last
decade. Immune checkpoint inhibitors blocking CTLA-4/B7 or PD-1/PD-L1 pathways have …

Background Anti-angiogenic therapy represents a promising strategy for non-small-cell lung
cancer (NSCLC) but its application in lung squamous cell carcinoma (SQC) is limited due to …

Glycolysis plays a crucial role in reprogramming the metastatic tumor microenvironment. A
series of lncRNAs have been identified to function as oncogenic molecules by regulating …

Background An increasing body of evidence has supported that long non-coding RNAs
(lncRNAs) can play as essential roles of various physiological process and pathological …

Abstract High oxidative stress, Th1/Th17 immune response, M1 macrophage inflammation,
and cell death are associated with cardiovascular diseases. Controlled oxidative stress …

Long noncoding RNAs (lncRNAs) show multiple functions, including immune response.
Recently, the immune‐related lncRNAs have been reported in some cancers. We first …

Asthma is a long-term inflammatory disease of the airways of the lungs refers changes that
occur in conjunction with, or as a result of, chronic airway inflammation. Airway remodeling …

Substantial evolution in cancer therapy has been witnessed lately, steering mainly towards
immunotherapeutic approaches, replacing or in combination with classical therapies …

Desmosomes play a key role in the regulation of cell adhesion and signaling. Dysregulation
of the desmosome complex is associated with the loss of epithelial cell polarity and …