The remarkable absorption capacity, biodegradability and non-toxicity of lignin
nanoparticles enable them to be appropriate vehicles for drug molecules and inorganic …

Bioactive substances, displaying excellent biocompatibility, chemical stability, and
processability, could be extensively applied in biomedicine and tissue engineering. In recent …

Background Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We
implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour …

Background Antiretroviral medications that are used as prophylaxis can prevent acquisition
of human immunodeficiency virus type 1 (HIV-1) infection. However, in clinical trials among …

Background Reproductive-age women need effective interventions to prevent the
acquisition of human immunodeficiency virus type 1 (HIV-1) infection. Methods We …

HIV prevalence is increasing worldwide because people on antiretroviral therapy are living
longer, although new infections decreased from 3· 3 million in 2002, to 2· 3 million in 2012 …

Antiretroviral-based strategies for HIV prevention have shown inconsistent results in women.
We investigated whether vaginal microbiota modulated tenofovir gel microbicide efficacy in …

Viral infections continue to cause considerable morbidity and mortality around the world.
Recent rises in these infections are likely due to complex and multifactorial external drivers …

Introduction HIV‐related stigma and discrimination continue to hamper efforts to prevent new
infections and engage people in HIV treatment, care and support programmes. The …

Abstract Background. Women in Africa, especially young women, have very high human
immunodeficiency virus (HIV) incidence rates that cannot be fully explained by behavioral …