Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Metabolic glycoengineering (MGE) is a technique for manipulating cellular metabolism to
modulate glycosylation. MGE is used to increase the levels of natural glycans and, more …

As one of the major types of biomacromolecules in the cell, glycans play essential functional
roles in various biological processes. Compared with proteins and nucleic acids, the …

Systematically dissecting the molecular basis of the cell surface as well as its related
biological activities is considered as one of the most cutting-edge fields in fundamental …

Radiotheranostics is a rapidly growing approach in personalized medicine, merging
diagnostic imaging and targeted radiotherapy to allow for the precise detection and …

CD22, a member of Siglec family of sialic acid binding proteins, has restricted expression on
B cells. Antibody‐based agents targeting CD22 or CD20 on B lymphoma and leukemia cells …

This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Among human milk oligosaccharides (HMOs), linear HMOs are synthesized through mature
but varied routes. Although branched HMOs can be synthesized by chemical, enzymatic, or …

Mucins represent a largely untapped class of polymeric building block for biomaterials,
therapeutics, and other biotechnology. Because the mucin polymer backbone is genetically …

Cellular glycosylation is characterized by chemical complexity and heterogeneity, which is
challenging to reproduce synthetically. Here we show chemoenzymatic synthesis on phage …