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[HTML][HTML] Genetics and molecular pathogenesis of gastric adenocarcinoma
Gastric cancer (GC) is globally the fifth most common cancer and third leading cause of
cancer death. A complex disease arising from the interaction of environmental and host …
cancer death. A complex disease arising from the interaction of environmental and host …
Mast cells, angiogenesis and lymphangiogenesis in human gastric cancer
Gastric cancer is diagnosed in nearly one million new patients each year and it remains the
second leading cause of cancer-related deaths worldwide. Although gastric cancer …
second leading cause of cancer-related deaths worldwide. Although gastric cancer …
[HTML][HTML] Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression
Understanding tumor microenvironment (TME) reprogramming in gastric adenocarcinoma
(GAC) progression may uncover novel therapeutic targets. Here, we performed single-cell …
(GAC) progression may uncover novel therapeutic targets. Here, we performed single-cell …
LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
J Tang, T Yan, Y Bao, C Shen, C Yu, X Zhu… - Nature …, 2019 - nature.com
Long non-coding RNAs (lncRNAs) contribute to colorectal cancer (CRC). However, the role
of lncRNAs in CRC metabolism, especially glucose metabolism remains largely unknown. In …
of lncRNAs in CRC metabolism, especially glucose metabolism remains largely unknown. In …
LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/β-catenin pathway
XZ Yang, TT Cheng, QJ He, ZY Lei, J Chi, Z Tang… - Molecular cancer, 2018 - Springer
Background Gastric cancer (GC) is a common malignancy and frequent cause of cancer-
related death. Long non-coding RNAs (lncRNAs) have emerged as important regulators and …
related death. Long non-coding RNAs (lncRNAs) have emerged as important regulators and …
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
Gastric cancer, a leading cause of cancer-related deaths, is a heterogeneous disease. We
aim to establish clinically relevant molecular subtypes that would encompass this …
aim to establish clinically relevant molecular subtypes that would encompass this …
LncRNA PVT1 promotes angiogenesis via activating the STAT3/VEGFA axis in gastric cancer
J Zhao, P Du, P Cui, Y Qin, C Hu, J Wu, Z Zhou… - Oncogene, 2018 - nature.com
Angiogenesis can aggravate gastric cancer progression. LncRNAs exert important roles in
regulating various cancer behaviors. However, the functions and mechanisms of lncRNAs in …
regulating various cancer behaviors. However, the functions and mechanisms of lncRNAs in …
LncRNA GClnc1 promotes gastric carcinogenesis and may act as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern
TT Sun, J He, Q Liang, LL Ren, TT Yan, TC Yu… - Cancer …, 2016 - aacrjournals.org
Long noncoding RNAs (lncRNA) play a role in carcinogenesis. However, the function of
lncRNAs in human gastric cancer remains largely unknown. In this study, we identified a …
lncRNAs in human gastric cancer remains largely unknown. In this study, we identified a …
Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma
Intratumoral heterogeneity (ITH) is a fundamental property of cancer; however, the origins of
ITH remain poorly understood. We performed single-cell transcriptome profiling of peritoneal …
ITH remain poorly understood. We performed single-cell transcriptome profiling of peritoneal …
Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review
MA Chiurillo - World journal of experimental medicine, 2015 - pmc.ncbi.nlm.nih.gov
Gastric cancer remains one of the most common cancers worldwide and one of the leading
cause for cancer-related deaths. Gastric adenocarcinoma is a multifactorial disease that is …
cause for cancer-related deaths. Gastric adenocarcinoma is a multifactorial disease that is …