Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations

IS Joung, TE Cheatham III - The journal of physical chemistry B, 2008 - ACS Publications
Alkali (Li+, Na+, K+, Rb+, and Cs+) and halide (F−, Cl−, Br−, and I−) ions play an important
role in many biological phenomena, roles that range from stabilization of biomolecular …

Parmbsc1: a refined force field for DNA simulations

I Ivani, PD Dans, A Noy, A Pérez, I Faustino… - Nature …, 2016 - nature.com
We present parmbsc1, a force field for DNA atomistic simulation, which has been
parameterized from high-level quantum mechanical data and tested for nearly 100 systems …

Frontiers in molecular dynamics simulations of DNA

A Pérez, FJ Luque, M Orozco - Accounts of chemical research, 2012 - ACS Publications
It has been known for decades that DNA is extremely flexible and polymorphic, but our
knowledge of its accessible conformational space remains limited. Structural data, primarily …

Refinement of the AMBER force field for nucleic acids: improving the description of α/γ conformers

A Pérez, I Marchán, D Svozil, J Sponer, TE Cheatham… - Biophysical journal, 2007 - cell.com
We present here the parmbsc0 force field, a refinement of the AMBER parm99 force field,
where emphasis has been made on the correct representation of the α/γ concerted rotation …

Twenty‐five years of nucleic acid simulations

TE Cheatham III, DA Case - Biopolymers, 2013 - Wiley Online Library
We present a brief, and largely personal, history of computer simulations of DNA and RNA
oligonucleotides, with an emphasis on duplex structures and the Amber force fields. Both …

[BOOK][B] The mathematics and mechanics of biological growth

A Goriely - 2017 - books.google.com
This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

Systematic comparison of the structural and dynamic properties of commonly used water models for molecular dynamics simulations

SP Kadaoluwa Pathirannahalage… - Journal of Chemical …, 2021 - ACS Publications
Water is a unique solvent that is ubiquitous in biology and present in a variety of solutions,
mixtures, and materials settings. It therefore forms the basis for all molecular dynamics …

Assessing the current state of amber force field modifications for DNA

R Galindo-Murillo, JC Robertson… - Journal of chemical …, 2016 - ACS Publications
The utility of molecular dynamics (MD) simulations to model biomolecular structure,
dynamics, and interactions has witnessed enormous advances in recent years due to the …

[BOOK][B] Nucleic acids in chemistry and biology

GM Blackburn - 2006 - books.google.com
The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

Conformational analysis of nucleic acids revisited: Curves+

R Lavery, M Moakher, JH Maddocks… - Nucleic acids …, 2009 - academic.oup.com
We describe Curves+, a new nucleic acid conformational analysis program which is
applicable to a wide range of nucleic acid structures, including those with up to four strands …