Current status and progress in research on dressing management for diabetic foot ulcer

P Jiang, Q Li, Y Luo, F Luo, Q Che, Z Lu… - Frontiers in …, 2023‏ - frontiersin.org
Diabetic foot ulcer (DFU) is a major complication of diabetes and is associated with a high
risk of lower limb amputation and mortality. During their lifetime, 19%–34% of patients with …

Designing hydrogels for controlled drug delivery

J Li, DJ Mooney - Nature Reviews Materials, 2016‏ - nature.com
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Recent advances in shear‐thinning and self‐healing hydrogels for biomedical applications

S Uman, A Dhand, JA Burdick - Journal of Applied Polymer …, 2020‏ - Wiley Online Library
Shear‐thinning and self‐healing hydrogels are being investigated in various biomedical
applications including drug delivery, tissue engineering, and 3D bioprinting. Such hydrogels …

Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

N Huebsch, E Lippens, K Lee, M Mehta, ST Koshy… - Nature materials, 2015‏ - nature.com
The effectiveness of stem cell therapies has been hampered by cell death and limited
control over fate. These problems can be partially circumvented by using macroporous …

Alginate: properties and biomedical applications

KY Lee, DJ Mooney - Progress in polymer science, 2012‏ - Elsevier
Alginate is a biomaterial that has found numerous applications in biomedical science and
engineering due to its favorable properties, including biocompatibility and ease of gelation …

Growth factor delivery: Defining the next generation platforms for tissue engineering

LMC Aguilar, SM Silva, SE Moulton - Journal of controlled Release, 2019‏ - Elsevier
Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …

Injectable alginate hydrogels for cell delivery in tissue engineering

SJ Bidarra, CC Barrias, PL Granja - Acta biomaterialia, 2014‏ - Elsevier
Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential
for use in biomedical applications. Their extracellular matrix-like features have been key …

Injectable and tunable gelatin hydrogels enhance stem cell retention and improve cutaneous wound healing

Y Dong, M Rodrigues, X Li, SH Kwon… - Advanced Functional …, 2017‏ - Wiley Online Library
Stem cells have shown substantial promise for various diseases in preclinical and clinical
trials. However, low cell engraftment rates significantly limit the clinical translation of stem …

Biomaterials for cell transplantation

N Mitrousis, A Fokina, MS Shoichet - Nature Reviews Materials, 2018‏ - nature.com
Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

K Lee, EA Silva, DJ Mooney - Journal of the Royal …, 2011‏ - royalsocietypublishing.org
The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …