Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Ionic liquid transdermal delivery system: Progress, prospects, and challenges

B Lu, T Liu, H Wang, C Wu, H Chen, Z Liu… - Journal of Molecular …, 2022 - Elsevier
In the drug delivery system, the transdermal drug delivery system has the advantages of
painless administration, avoiding the first-pass metabolism, sustained therapeutic effect, and …

Cyclosporine-loaded micelles for ocular delivery: Investigating the penetration mechanisms

M Ghezzi, I Ferraboschi, A Delledonne… - Journal of Controlled …, 2022 - Elsevier
Cyclosporine is an immunomodulatory drug commonly used for the treatment of mild-to-
severe dry eye syndrome as well as intermediate and posterior segment diseases as uveitis …

Liquid formulations based on ionic liquids in biomedicine

WX Zhang, YR Gao, R Xue, W Nguyen, W Chen… - Materials Today …, 2023 - Elsevier
Ionic liquids (ILs) are innovative ionic solvents with unique properties of negligible vapor
pressure, favorable conductivity, high thermal and chemical stability as well as self …

pH and its applications in targeted drug delivery

S Abdella, F Abid, SH Youssef, S Kim, F Afinjuomo… - Drug Discovery …, 2023 - Elsevier
Highlights•pH is vital for the normal functioning of the body.•Drug targeting has been widely
used to increase efficacy and reduce adverse effects.•pH variation in different tissues and …

Recent advances in surface-active ionic liquid-assisted self-assembly systems for drug delivery

RM Moshikur, MK Ali, M Moniruzzaman… - Current Opinion in Colloid …, 2021 - Elsevier
Surface-active ionic liquids (SAILs) are receiving growing interest as environmentally
friendly designer surfactants for various applications, including drug formulation and …

Local chemotherapy as an adjuvant treatment in unresectable squamous cell carcinoma: what do we know so far?

L Bennardo, F Bennardo, A Giudice, M Passante… - Current …, 2021 - mdpi.com
Background: Squamous cell carcinoma (SCC) is one of the most common cancers involving
skin and oral mucosa. Although this condition's gold-standard treatment is the surgical …

Designing temporal-and spatial-control multifunctional nanoformulations for synergistic photodynamic–enhanced tumour immunotherapy

P Zhang, Y Cui, Y Wang - Nano Today, 2023 - Elsevier
The combination of light-activated therapy and immunotherapy is attracting considerable
attention in tumour therapy. However, increasing the safety, quality, and durability of light …

Ionic liquids in pharmaceutical and biomedical applications: A review

Y Zhuo, HL Cheng, YG Zhao, HR Cui - Pharmaceutics, 2024 - mdpi.com
The unique properties of ionic liquids (ILs), such as structural tunability, good solubility,
chemical/thermal stability, favorable biocompatibility, and simplicity of preparation, have led …

Ionic liquids: Formulation avenues, drug delivery and therapeutic updates

NR Jadhav, SP Bhosale, SS Bhosale, SD Mali… - Journal of Drug Delivery …, 2021 - Elsevier
Background Numerous challenges are faced during formulation and biopharmaceutics of
newly developed drug molecules due to polymorphic conversion, poor bioavailability …