C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

Introduction: Spirooxindole, a unique and versatile scaffold, has been widely studied in
some fields such as pharmaceutical chemistry and synthetic chemistry. Especially in the …

This Review provides an in‐depth account of the synthesis of spirocyclic indolenines. Over
the last 77 years, a wide array of diverse synthetic methods has been developed in order to …

First-row transition-metal-mediated reactions constitute an important and growing area of
research due to the low cost, low toxicity, and exceptional synthetic versatility of these …

Spiro [azetidine‐indolines] are important scaffolds in diverse bioactive compounds. Current
efforts to synthesize spiro [azetidine‐indolines] are limited to chiral spiro [azetidine‐2, 3 …

A Cu-catalyzed protocol for cross-dehydrogenative coupling of benzofuranones with
quinolines, indoles, carbazoles, and thiophene, which furnishes highly functionalized 3, 3 …

An intramolecular-dehydrogenative-coupling (IDC) using “transition-metal-free” oxidation
conditions has been achieved to synthesize a variety of 2-oxindoles bearing an all-carbon …

Oxindoles and β-lactams are attractive structural motifs because of their unique biological
importance. However, the fusion of the two moieties featuring 3, 3′-spirocyclic scaffolds is a …

We describe a direct construction of all-carbon quaternary centers from secondary C (sp3)–
H substrates through a dehydrogenative cross-coupling reaction. Using FeCl2· 4H2O as the …

Asymmetric intramolecular direct hydroarylation of α‐ketoamides gives various types of
optically active 3‐substituted 3‐hydroxy‐2‐oxindoles in high yields with complete …