Cholinergic receptors represent a promising class of diagnostic and therapeutic targets due
to their significant involvement in cognitive decline associated with neurological disorders …

The neurotransmitter acetylcholine (ACh) plays a central role in the regulation of multiple
cognitive and behavioral processes, including attention, learning, memory, motivation …

The study of nicotinic acetylcholine receptors (nAChRs) has significantly progressed in the
last decade, due to a) the improved techniques available for structural studies; b) the …

On average, humans spend about 26 years of their life slee**. Increased sleep duration
and quality has been linked to reduced disease risk; however, the cellular and molecular …

The cholinergic system is a critical mediator of cognition in animals. People who smoke
cigarettes exhibit cognitive deficits, especially during quit attempts. Few studies jointly …

Cigarette smoking is the single most significant cause of preventable death in the world.
Tobacco smoking causes exposure to thousands of chemicals and disrupts biological …

With aging populations in many countries, the prevalence of neurodegenerative diseases is
expected to increase in the upcoming decades. Currently, no disease modifying therapies …

Alzheimer's disease (AD) continues to pose a growing public health threat across the globe,
with its progression leading to severe cognitive decline. A feature of this condition is the …