Biomolecular condensates compartmentalize and regulate assemblies of biomolecules
engaged in vital physiological processes in cells. Specific proteins and nucleic acids …

The distinct prion-like domains (PrLDs) of FUS and TDP-43, modulate phase transitions that
result in condensates with a range of material states. These assemblies are implicated in …

Condensed states of proteins, including liquid-like membraneless organelles and solid-like
aggregates, contribute in fundamental ways to the organisation and function of the cell …

Protein condensates are distinct structures assembled in living cells that concentrate
molecules via phase separation in a confined subcellular compartment. In the past decade …

Biomolecular condensates that form via phase separation are increasingly regarded as
coordinators of cellular reactions that regulate a wide variety of biological phenomena …

Aggregation of the microtubule-associated protein tau plays a major role in Alzheimer's
disease and several other neurodegenerative disorders. An exciting recent development is …

The assembly of biomolecules into condensates is a fundamental process underlying the
organisation of the intracellular space and the regulation of many cellular functions …

A multitude of cellular processes involve biomolecular condensates, which has led to the
suggestion that diverse pathogenic mutations may dysregulate condensates. Although proof …

Leveraging complex coacervation of a polycation and a bivalent anion with aggregation-
induced emission characteristics, we accomplish eight basic logic operations with …

Biomolecular condensates organize cellular functions in the absence of membranes. These
membraneless organelles can form through liquid–liquid phase separation coalescing RNA …