Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

Introduction: Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This
USFDA-approved polymer is popular due to its tunable properties and well-established …

There is considerable current interest in polymerization-induced self-assembly (PISA) via
reversible addition–fragmentation chain transfer (RAFT) polymerization as a versatile and …

Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …

Polymersomes, the structural analogues of liposomes, are hollow structures enclosed by a
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …

Efficient viral or nonviral delivery of nucleic acids is the key step of genetic nanomedicine.
Both viral and synthetic vectors have been successfully employed for genetic delivery with …

Abstract pH-responsive polymers contain ionic functional groups as pendants in their
structure. The total number of charged groups on polymer chains determines the overall …

Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal
antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential …

Responsive polymer materials can adapt to surrounding environments, regulate transport of
ions and molecules, change wettability and adhesion of different species on external stimuli …

This Perspective describes the recent developments of polymerization-induced self-
assembly of amphiphilic block copolymers based on controlled/living free-radical …