Pathophysiology of type 2 diabetes mellitus

U Galicia-Garcia, A Benito-Vicente, S Jebari… - International journal of …, 2020 - mdpi.com
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

[HTML][HTML] Skin wound healing: normal macrophage function and macrophage dysfunction in diabetic wounds

SM Aitcheson, FD Frentiu, SE Hurn, K Edwards… - Molecules, 2021 - mdpi.com
Macrophages play a prominent role in wound healing. In the early stages, they promote
inflammation and remove pathogens, wound debris, and cells that have apoptosed. Later in …

Epidemiology and pathophysiology of COVID-19-associated mucormycosis: India versus the rest of the world

V Muthu, SM Rudramurthy, A Chakrabarti, R Agarwal - Mycopathologia, 2021 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a concerning
resurgence of mucormycosis. More than 47,000 cases of mucormycosis were reported in …

[HTML][HTML] Diabetes, infection risk and COVID-19

S Erener - Molecular metabolism, 2020 - Elsevier
Background Individuals with diabetes are at a greater risk of hospitalization and mortality
resulting from viral, bacterial, and fungal infections. The coronavirus disease-2019 (COVID …

[HTML][HTML] Polymicrobial infections and biofilms: clinical significance and eradication strategies

VT Anju, S Busi, M Imchen, R Kumavath, MS Mohan… - Antibiotics, 2022 - mdpi.com
Biofilms are population of cells growing in a coordinated manner and exhibiting resistance
towards hostile environments. The infections associated with biofilms are difficult to control …

Self-healing hydrogels based on biological macromolecules in wound healing: A review

P Yang, Z Li, B Fang, L Liu - International Journal of Biological …, 2023 - Elsevier
The complete healing of skin wounds has been a challenge in clinical treatment. Self-
healing hydrogels are special hydrogels formed by distinctive physicochemically reversible …

The interplay between immunosenescence and age-related diseases

F Barbé-Tuana, G Funchal, CRR Schmitz… - Seminars in …, 2020 - Springer
The aging immune system (immunosenescence) has been implicated with increased
morbidity and mortality in the elderly. Of note, T cell aging and low-grade inflammation …

Phagocytosis: an immunobiologic process

S Gordon - Immunity, 2016 - cell.com
It has been a century since the death of Élie Metchnikoff, who championed the role of
phagocytosis in cellular immunity. Whereas others had observed the uptake of particles by …

[HTML][HTML] Impact of obesity and metabolic syndrome on immunity

CJ Andersen, KE Murphy, ML Fernandez - Advances in Nutrition, 2016 - Elsevier
Obesity is associated with metabolic disturbances that cause tissue stress and dysfunction.
Obese individuals are at a greater risk for chronic disease and often present with clinical …