Our cells are comprised of billions of proteins, lipids, and other small molecules packed into
their respective subcellular organelles, with the daunting task of maintaining cellular …

Aging is a continuous process over time that is mainly related to natural alterations in
mechanical–biological processes. This phenomenon is due to several factors, including the …

Background and purpose Clinical trials in spinocerebellar ataxia type 3 (SCA3) will require
biomarkers for use as outcome measures. Methods To evaluate total tau (t‐tau), glial …

This review summarizes our current knowledge of human disease-relevant genetic variants
within the family of voltage gated Ca2+ channels. Ca2+ channelopathies cover a wide …

Huntington's disease (HD) is a debilitating neurodegenerative genetic disorder caused by
an expanded polyglutamine-coding (CAG) trinucleotide repeat in the huntingtin (HTT) gene …

Neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and
amyotrophic lateral sclerosis, are characterized by a progressive loss of selective neuron …

Neural mitochondrial dysfunction, neural oxidative stress, chronic neuroinflammation, toxic
protein accumulation, and neural apoptosis are common causes of neurodegeneration …

Huntington's disease (HD) is a progressive neurodegenerative disease characterized by
mutations in the huntingtin gene (mHtt), causing an unstable repeat of the CAG trinucleotide …

The spectrum of neurodegenerative diseases known today is quite extensive. The
complexities of their research and treatment lie not only in their diversity. Even many years of …

Reports on phase separation and amyloid formation for multiple proteins and aggregation-
prone peptides are recurrently used to explore the molecular mechanisms associated with …