[HTML][HTML] Antioxidant, anti-inflammatory, anti-menopausal, and anti-cancer effects of lignans and their metabolites

WY Jang, MY Kim, JY Cho - International journal of molecular sciences, 2022 - mdpi.com
Since chronic inflammation can be seen in severe, long-lasting diseases such as cancer,
there is a high demand for effective methods to modulate inflammatory responses. Among …

[HTML][HTML] Lignans as pharmacological agents in disorders related to oxidative stress and inflammation: chemical synthesis approaches and biological activities

DI Osmakov, AP Kalinovskii, OA Belozerova… - International journal of …, 2022 - mdpi.com
Plant lignans exhibit a wide range of biological activities, which makes them the research
objects of potential use as therapeutic agents. They provide diverse naturally-occurring …

Insights into antioxidant activities and anti-skin-aging potential of callus extract from Centella asiatica (L.)

V Buranasudja, D Rani, A Malla, K Kobtrakul… - Scientific Reports, 2021 - nature.com
Formation of oxidative stress in dermal fibroblasts plays crucial roles in aging processes of
skin. The use of phytochemicals that can promote capacity of fibroblasts to combat oxidative …

[HTML][HTML] Antifungal activity of human cathelicidin LL-37, a membrane disrupting peptide, by triggering oxidative stress and cell cycle arrest in Candida auris

IA Rather, JSM Sabir, AH Asseri, S Ali - Journal of Fungi, 2022 - mdpi.com
Candida auris, an evolving multidrug-resistant pathogenic yeast, is known for causing
severe invasive infections associated with high mortality rates in hospitalized individuals …

Empagliflozin alleviates renal inflammation and oxidative stress in streptozotocin-induced diabetic rats partly by repressing HMGB1-TLR4 receptor axis

ZA Jigheh, AG Haghjo, H Argani… - Iranian journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Objective (s): Empagliflozin, a sodium-glucose cotransporter-2 (SGLT-2) inhibitor,
possesses verified anti-inflammatory and anti-oxidative stress effects against diabetic …

The what and who of dietary lignans in human health: Special focus on prooxidant and antioxidant effects

S Soleymani, S Habtemariam, R Rahimi… - Trends in Food Science & …, 2020 - Elsevier
Background Lignans are large group of polyphenols that are formed by the coupling of two
coniferyl alcohol residues. Based on their origin, lignans are broadly grouped into plant …

Particulate matter induces oxidative stress and ferroptosis in human lung epithelial cells

Y Ahn, YH Yim, HM Yoo - Toxics, 2024 - mdpi.com
Numerous toxicological studies have highlighted the association between urban particulate
matter (PM) and increased respiratory infections and lung diseases. The adverse impact on …

[HTML][HTML] Anti–Inflammatory and Antioxidant Properties of the Ethanol Extract of Clerodendrum Cyrtophyllum Turcz in Copper Sulfate-Induced Inflammation in …

TH Nguyen, HD Le, T Nguyen Thi Kim, H Pham The… - Antioxidants, 2020 - mdpi.com
Oxidative stress and inflammation are commonly present in many chronic diseases. These
responses are closely related to pathophysiological processes. The inflammatory process …

[HTML][HTML] Terpenoid-Rich Extract of Dillenia indica L. Bark Displays Antidiabetic Action in Insulin-Resistant C2C12 Cells and STZ-Induced Diabetic Mice by Attenuation …

BR Song, MB Alam, SH Lee - Antioxidants, 2022 - mdpi.com
Insulin resistance (IR) plays a key role in the pathogenesis and clinical outcome of patients
with multiple diseases and diabetes. In this study, we examined the antidiabetic effects of a …

The promising antioxidant effects of lignans: Nrf2 activation comes into view

EHM Hassanein, HS Althagafy, MA Baraka… - Naunyn-Schmiedeberg's …, 2024 - Springer
Lignans are biologically active compounds widely distributed, recognized, and identified in
seeds, fruits, and vegetables. Lignans have several intriguing bioactivities, including anti …