Roles of neutrophil granule proteins in orchestrating inflammation and immunity

A Othman, M Sekheri, JG Filep - The FEBS journal, 2022 - Wiley Online Library
Neutrophil granulocytes form the first line of host defense against invading pathogens and
tissue injury. They are rapidly recruited from the blood to the affected sites, where they …

LPS-induced cytokine production in human monocytes and macrophages

M Rossol, H Heine, U Meusch, D Quandt… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Lipopolysaccharide (LPS) from Gram-negative bacteria is one of the most potent innate
immune-activating stimuli known. Here we review the current understanding of LPS effects …

Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases

M Akdis, S Burgler, R Crameri, T Eiwegger… - Journal of allergy and …, 2011 - Elsevier
Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

β-Glucan-induced trained immunity protects against Leishmania braziliensis infection: a crucial role for IL-32

JC Dos Santos, AMB de Figueiredo, MVT Silva… - Cell reports, 2019 - cell.com
American tegumentary leishmaniasis is a vector-borne parasitic disease caused by
Leishmania protozoans. Innate immune cells undergo long-term functional reprogramming …

Aptamers against pro-and anti-inflammatory cytokines: a review

M Boshtam, S Asgary, S Kouhpayeh, L Shariati… - Inflammation, 2017 - Springer
Inflammatory disorders result from continuous inflammation in injured sites. Many molecules
are involved in this process; the inhibition of which could prevent the inflammation …

Advanced drug delivery and therapeutic strategies for tuberculosis treatment

A Nair, A Greeny, A Nandan, RK Sah, A Jose… - Journal of …, 2023 - Springer
Tuberculosis (TB) remains a significant global health challenge, necessitating innovative
approaches for effective treatment. Conventional TB therapy encounters several limitations …

Cytokines in the pathogenesis of rheumatoid arthritis: new players and therapeutic targets

A Alunno, F Carubbi, R Giacomelli, R Gerli - BMC rheumatology, 2017 - Springer
In recent years, the landscape of pro-and anti-inflammatory cytokines has rapidly expanded
with the identification of new members proven to be involved at different extent in the …

Tim4 deficiency reduces CD301b+ macrophage and aggravates periodontitis bone loss

Z Wang, H Zeng, C Wang, J Wang, J Zhang… - International Journal of …, 2024 - nature.com
Periodontitis is a common chronic inflammatory disease that causes the periodontal bone
destruction and may ultimately result in tooth loss. With the progression of periodontitis, the …

The Jekyll and Hyde functions of caspases

HY Caroline, J Yuan - Developmental cell, 2009 - cell.com
Apoptosis is an ancient form of regulated cell death that functions under pathological and
nonpathological contexts in all metazoans. More than a decade of intense research has led …

IL‐32: a novel pluripotent inflammatory interleukin, towards gastric inflammation, gastric cancer, and chronic rhino sinusitis

MB Khawar, MH Abbasi, N Sheikh - Mediators of inflammation, 2016 - Wiley Online Library
A vast variety of nonstructural proteins have been studied for their key roles and involvement
in a number of biological phenomenona. Interleukin‐32 is a novel cytokine whose presence …