[HTML][HTML] Colorectal liver metastases: Current management and future perspectives
The liver is the commonest site of metastatic disease for patients with colorectal cancer, with
at least 25% develo** colorectal liver metastases (CRLM) during the course of their …
at least 25% develo** colorectal liver metastases (CRLM) during the course of their …
A framework for the development of effective anti-metastatic agents
RL Anderson, T Balasas, J Callaghan… - Nature Reviews …, 2019 - nature.com
Most cancer-related deaths are a result of metastasis, and thus the importance of this
process as a target of therapy cannot be understated. By asking 'how can we effectively treat …
process as a target of therapy cannot be understated. By asking 'how can we effectively treat …
Implications of the pattern of disease recurrence on survival following pancreatectomy for pancreatic ductal adenocarcinoma
Background After radical resection of pancreatic ductal adenocarcinoma (PDAC),
approximately 80% of patients will develop disease recurrence. It remains unclear to what …
approximately 80% of patients will develop disease recurrence. It remains unclear to what …
Conditional recurrence-free survival after resection of colorectal liver metastases: persistent deleterious association with RAS and TP53 co-mutation
Background Conditional recurrence-free survival (RFS) probability, that is, the probability of
remaining recurrence-free after a given interval without recurrence, has not been reported …
remaining recurrence-free after a given interval without recurrence, has not been reported …
Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases
K Bolhuis, I van't Erve, C Mijnals… - …, 2021 - thelancet.com
Background Recurrence rates after resection of colorectal cancer liver metastases (CRLM)
are high and correlate with worse survival. Postoperative circulating tumour DNA (ctDNA) is …
are high and correlate with worse survival. Postoperative circulating tumour DNA (ctDNA) is …
Regional therapy for colorectal cancer liver metastases: which modality and when?
For patients with unresectable colorectal liver metastases (uCRLM), regional therapies
leverage the unique, dual blood supply to the liver; the hepatic artery is the main blood …
leverage the unique, dual blood supply to the liver; the hepatic artery is the main blood …
Circulating tumor DNA as a marker of minimal residual disease after radical resection of colorectal liver metastases
F Marmorino, M Prisciandaro, M Giordano… - JCO precision …, 2022 - ascopubs.org
PURPOSE Prognostic tools to estimate the risk of relapse for patients with liver-limited
metastatic colorectal cancer (LL-mCRC) undergoing resection with curative intent are …
metastatic colorectal cancer (LL-mCRC) undergoing resection with curative intent are …
[HTML][HTML] Perioperative outcomes comparing laparoscopic with open repeat liver resection for post-hepatectomy recurrent liver cancer: a systematic review and meta …
Background Repeat laparoscopic hepatectomy (LRH) offers an option for recurrent tumors in
liver remnants following an initial liver resection of recurrent hepatocellular carcinoma …
liver remnants following an initial liver resection of recurrent hepatocellular carcinoma …
Fibrinogen–albumin ratio index (FARI): a more promising inflammation-based prognostic marker for patients undergoing hepatectomy for colorectal liver metastases
YY Wang, ZZ Liu, D Xu, M Liu, K Wang… - Annals of Surgical …, 2019 - Springer
Background Systemic inflammation response is involved in the development and
progression of cancers. This study aimed to evaluate the prognostic value of a preoperative …
progression of cancers. This study aimed to evaluate the prognostic value of a preoperative …
The prognostic utility of preoperative neutrophil-to-lymphocyte ratio (NLR) in patients with colorectal liver metastasis: a systematic review and meta-analysis
Y Li, T Xu, X Wang, X Jia, M Ren, X Wang - Cancer Cell International, 2023 - Springer
The neutrophil-to-lymphocyte ratio is used to reflect body's inflammatory status with
prognostic value in different cancers. We aimed to investigate the influence of preoperative …
prognostic value in different cancers. We aimed to investigate the influence of preoperative …