Advances in COVID-19 mRNA vaccine development

E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …

SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact

M Lipsitch, F Krammer, G Regev-Yochay… - Nature Reviews …, 2022 - nature.com
Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant was first identified in November 2021 in
Botswana and South Africa,–. It has since spread to many countries and is expected to …

Effectiveness of BNT162b2 vaccine against omicron variant in South Africa

S Collie, J Champion, H Moultrie… - New England Journal …, 2022 - Mass Medical Soc
Preliminary Data on Vaccine Protection against Omicron Using a test-negative study design
focused on the period of dominance of the B. 1.1. 529 (omicron) variant in South Africa …

[HTML][HTML] Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV …

APS Munro, L Janani, V Cornelius, PK Aley… - The Lancet, 2021 - thelancet.com
Background Few data exist on the comparative safety and immunogenicity of different
COVID-19 vaccines given as a third (booster) dose. To generate data to optimise selection …

Homologous and heterologous Covid-19 booster vaccinations

RL Atmar, KE Lyke, ME Deming… - … England Journal of …, 2022 - Mass Medical Soc
Background Although the three vaccines against coronavirus disease 2019 (Covid-19) that
have received emergency use authorization in the United States are highly effective …

[HTML][HTML] Waning 2-dose and 3-dose effectiveness of mRNA vaccines against COVID-19–associated emergency department and urgent care encounters and …

JM Ferdinands - MMWR. Morbidity and mortality weekly report, 2022 - cdc.gov
Vaccine effectiveness (VE) against COVID-19–associated emergency department/urgent
care (ED/UC) visits and hospitalizations was higher after the third dose than after the second …

Effect of mRNA vaccine boosters against SARS-CoV-2 Omicron infection in Qatar

LJ Abu-Raddad, H Chemaitelly… - … England Journal of …, 2022 - Mass Medical Soc
Background Waning of vaccine protection against coronavirus disease 2019 (Covid-19) and
the emergence of the omicron (or B. 1.1. 529) variant of the severe acute respiratory …

Effectiveness of COVID-19 booster vaccines against COVID-19-related symptoms, hospitalization and death in England

N Andrews, J Stowe, F Kirsebom, S Toffa… - Nature medicine, 2022 - nature.com
Booster vaccination with messenger RNA (mRNA) vaccines has been offered to adults in
England starting on 14 September 2021. We used a test-negative case–control design to …

[HTML][HTML] Effectiveness of a third dose of mRNA vaccines against COVID-19–associated emergency department and urgent care encounters and hospitalizations …

MG Thompson - MMWR. Morbidity and mortality weekly report, 2022 - cdc.gov
VE was significantly higher among patients who received their second mRNA COVID-19
vaccine dose< 180 days before medical encounters compared with those vaccinated≥ 180 …