Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

Tissue clearing of gross anatomical samples was first described more than a century ago
and has only recently found widespread use in the field of microscopy. This renaissance has …

TrackMate is an automated tracking software used to analyze bioimages and is distributed
as a Fiji plugin. Here, we introduce a new version of TrackMate. TrackMate 7 is built to …

We present LABKIT, a user-friendly Fiji plugin for the segmentation of microscopy image
data. It offers easy to use manual and automated image segmentation routines that can be …

Abstract Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate
immune system and widely studied in contexts of infection and autoimmunity. Studies …

Microglia and border-associated macrophages (BAMs) are brain-resident self-renewing
cells. Here, we examined the fate of microglia, BAMs, and recruited macrophages upon …

Plant roots exhibit plasticity in their branching patterns to forage efficiently for
heterogeneously distributed resources, such as soil water. The xerobranching response …

Tissue development and disease lead to changes in cellular organization, nuclear
morphology, and gene expression, which can be jointly measured by spatial transcriptomic …

When solutions and slurries are directionally solidified, complex dynamics of solvent crystal
growth and solvent templating determine the final hierarchical architecture of the freeze-cast …

Advanced imaging techniques provide holistic observations of complicated biological
phenomena across multiple scales while posing great challenges to data analysis. We …