[HTML][HTML] Towards the year 2049: The next 25 years of occupational health and safety research

A Ropponen, R Rugulies… - Scandinavian Journal of …, 2024‏ - pmc.ncbi.nlm.nih.gov
Objective In this discussion paper, we close our 2024 series reflecting on the successes,
failures, and promises of occupational health and safety research in celebration of the 50th …

[HTML][HTML] The impact of gut microbiota on the occurrence, treatment, and prognosis of ischemic stroke

L Chen, X Wang, S Wang, W Liu, Z Song, H Liao - Neurobiology of Disease, 2025‏ - Elsevier
Ischemic stroke (IS) is a cerebrovascular disease that predominantly affects middle-aged
and elderly populations, exhibiting high mortality and disability rates. At present, the …

Intravenous glibenclamide for cerebral oedema after large hemispheric stroke (CHARM): a phase 3, double-blind, placebo-controlled, randomised trial

KN Sheth, GW Albers, JL Saver, BCV Campbell… - The Lancet …, 2024‏ - thelancet.com
Background No treatment is available to prevent brain oedema, which can occur after a
large hemispheric infarction. Glibenclamide has previously been shown to improve …

Global burden of stroke: dynamic estimates to inform action

S Wu, M Liu - The Lancet Neurology, 2024‏ - thelancet.com
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 1 provides dynamic
estimates of disease burden and up-to-date evidence to inform health-care policy. The latest …

[HTML][HTML] Sex and Age-Dependent Effects of miR-15a/16-1 Antagomir on Ischemic Stroke Outcomes

X Huang, S Li, N Qiu, A Ni, T **ong, J Xue… - International journal of …, 2024‏ - mdpi.com
Ischemic stroke is a leading cause of disability and mortality worldwide. Recently, increasing
evidence implicates microRNAs (miRs) in the pathophysiology of ischemic stroke. Studies …

[HTML][HTML] Histopathological Analysis of Lipopolysaccharide-Induced Liver Inflammation and Thrombus Formation in Mice: The Protective Effects of Aspirin

H Saitoh, M Sakaguchi, F Miruno, N Muramatsu… - Current Issues in …, 2024‏ - mdpi.com
Hepatitis, a significant medical concern owing to its potential to cause acute and chronic
liver disease, necessitates early intervention. In this study, we aimed to elucidate the …

[HTML][HTML] Evaluating Machine Learning Models for Stroke Prognosis and Prediction in Atrial Fibrillation Patients: A Comprehensive Meta-Analysis

B Goh, SMM Bhaskar - Diagnostics, 2024‏ - pmc.ncbi.nlm.nih.gov
Background/Objective: Atrial fibrillation (AF) complicates the management of acute ischemic
stroke (AIS), necessitating precise predictive models to enhance clinical outcomes. This …

[HTML][HTML] Risk and impact of stroke across 38 countries and territories of the Americas from 1990 to 2021: a population-based trends analysis from the Global Burden of …

R Martinez, P Muñoz-Venturelli, P Ordunez… - The Lancet Regional …, 2025‏ - thelancet.com
Background Despite substantial declines in burden over time, stroke remains a public health
threat in the Americas. This study aimed to assess the current magnitude, trends, and …

[HTML][HTML] Nanoparticles for Thrombolytic Therapy in Ischemic Stroke: A Systematic Review and Meta-Analysis of Preclinical Studies

J Prego-Domínguez, F Laso-García, N Palomar-Alonso… - Pharmaceutics, 2025‏ - mdpi.com
Background: Recombinant tissue plasminogen activator (rtPA) remains the standard
thrombolytic treatment for ischemic stroke. Different types of nanoparticles have emerged as …

Global regional and national burden of intracerebral hemorrhage between 1990 and 2021

Z Wang, M Wan, J Tai, Y Wang, M Yin - Scientific Reports, 2025‏ - nature.com
Intracerebral hemorrhage (ICH) represents one of the most devastating forms of stroke,
characterized by spontaneous bleeding into the brain parenchyma. This neurological …