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EMP1, EMP 2, and EMP3 as novel therapeutic targets in human cancer
YW Wang, HL Cheng, YR Ding, LH Chou… - Biochimica et Biophysica …, 2017 - Elsevier
The epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, and EMP3) belong to the
peripheral myelin protein 22-kDa (PMP22) gene family, which consists of at least seven …
peripheral myelin protein 22-kDa (PMP22) gene family, which consists of at least seven …
Unraveling the structures, functions and mechanisms of epithelial membrane protein family in human cancers
N Zhang, HP Zhu, W Huang, X Wen, X **e… - … hematology & oncology, 2022 - Springer
Abstract Peripheral myelin protein 22 (PMP22) and epithelial membrane proteins (EMP-1,-2,
and-3) belong to a small hydrophobic membrane protein subfamily, with four …
and-3) belong to a small hydrophobic membrane protein subfamily, with four …
Cancer-associated fibroblasts (CAFs) gene signatures predict outcomes in breast and prostate tumor patients
Background Over the last two decades, tumor-derived RNA expression signatures have
been developed for the two most commonly diagnosed tumors worldwide, namely prostate …
been developed for the two most commonly diagnosed tumors worldwide, namely prostate …
89Zr-ImmunoPET for the Specific Detection of EMP2-Positive Tumors
Abstract Epithelial membrane protein-2 (EMP2) is upregulated in a number of tumors and
therefore remains a promising target for mAb-based therapy. In the current study, image …
therefore remains a promising target for mAb-based therapy. In the current study, image …
A-to-I RNA editing shows dramatic up-regulation in osteosarcoma and broadly regulates tumor-related genes by altering microRNA target regions
F Ge, X Cao, Y Jiang - Journal of Applied Genetics, 2023 - Springer
Abstract A-to-I RNA editing is a prevalent type of RNA modification in animals. The
dysregulation of RNA editing has led to multiple human cancers. However, the role of RNA …
dysregulation of RNA editing has led to multiple human cancers. However, the role of RNA …
A novel model to combine clinical and pathway-based transcriptomic information for the prognosis prediction of breast cancer
Breast cancer is the most common malignancy in women worldwide. With the increasing
awareness of heterogeneity in breast cancers, better prediction of breast cancer prognosis is …
awareness of heterogeneity in breast cancers, better prediction of breast cancer prognosis is …
[HTML][HTML] The pivotal roles of the epithelial membrane protein family in cancer invasiveness and metastasis
MKB Ahmat Amin, A Shimizu, H Ogita - Cancers, 2019 - mdpi.com
The members of the family of epithelial membrane proteins (EMPs), EMP1, EMP2, and
EMP3, possess four putative transmembrane domain structures and are composed of …
EMP3, possess four putative transmembrane domain structures and are composed of …
Chromatin interaction networks revealed unique connectivity patterns of broad H3K4me3 domains and super enhancers in 3D chromatin
Broad domain promoters and super enhancers are regulatory elements that govern cell-
specific functions and harbor disease-associated sequence variants. These elements are …
specific functions and harbor disease-associated sequence variants. These elements are …
[HTML][HTML] Epithelial membrane protein 2 suppresses non-small cell lung cancer cell growth by inhibition of MAPK pathway
Y Ma, DC Schröder, M Nenkov, MN Rizwan… - International journal of …, 2021 - mdpi.com
Epithelial membrane proteins (EMP1-3) are involved in epithelial differentiation and
carcinogenesis. Dysregulated expression of EMP2 was observed in various cancers, but its …
carcinogenesis. Dysregulated expression of EMP2 was observed in various cancers, but its …
Integrating the characteristic genes of macrophage pseudotime analysis in single-cell RNA-seq to construct a prediction model of atherosclerosis
Z Tian, S Yang - Aging (Albany Ny), 2023 - pmc.ncbi.nlm.nih.gov
Background: Macrophages play an important role in the occurrence and development of
atherosclerosis. However, few existing studies have deliberately analyzed the changes in …
atherosclerosis. However, few existing studies have deliberately analyzed the changes in …