The field of prebiotic chemistry has been dedicated over decades to finding abiotic routes
towards the molecular components of life. There is nowadays a handful of prebiotically …

Although aqueous solutions are considered to be sustainable, environmentally friendly
reaction media, their use is often limited by poor reactant solubility. This limitation can be …

The ability to modify multiple genetic elements simultaneously would help to elucidate and
control the gene interactions and networks underlying complex cellular functions. However …

Cell membranes are a key element of life because they keep the genetic material and
metabolic machinery together. All present cell membranes are made of phospholipids, yet …

Replication, heredity, and evolution are characteristic of Life. We and others have postulated
that the reconstruction of a synthetic living system in the laboratory will be contingent on the …

Understanding the behavior of complex chemical reaction networks and how environmental
conditions can modulate their organization as well as the associated outcomes may take …

Conspectus Central to the quest of understanding the emergence of life is to uncover the
role of metals, particularly iron, in sha** prebiotic chemistry. Iron, as the most abundant of …

Highlights•Organisms need to adapt to changes in metabolic demand/environmental
conditions to survive.•Those adaptations require coordinated adjustments in energy …

One of the biggest challenges in modern chemistry is the preparation of synthetic materials
with life-like behavior for the assembly of artificial cells. In recent years, numerous artificial …

Phospholipids are essential components of biological membranes and are involved in cell
signalization, in several enzymatic reactions, and in energy metabolism. In addition …