Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health
BACKGROUND The essential amino acid tryptophan is a substrate for the generation of
several bioactive compounds with important physiological roles. Only a small fraction of …
several bioactive compounds with important physiological roles. Only a small fraction of …
Metabolomics in infectious diseases and drug discovery
Metabolomics has emerged as an invaluable tool that can be used along with genomics,
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …
CD4: CD8 ratio as a frontier marker for clinical outcome, immune dysfunction and viral reservoir size in virologically suppressed HIV‐positive patients
Methods A comprehensive review of the English‐language publications was implemented.
We searched PubMed, JSTOR and Scopus electronic databases with keyword combinations …
We searched PubMed, JSTOR and Scopus electronic databases with keyword combinations …
The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation
Gut dysbiosis, namely dysregulation of the intestinal microbiota, and increased gut
permeability lead to enhanced inflammation and are commonly seen in chronic conditions …
permeability lead to enhanced inflammation and are commonly seen in chronic conditions …
Oncogenic effects of HIV-1 proteins, mechanisms behind
Simple Summary People living with human immunodeficiency virus type 1 (HIV-1)(PLWH)
are at increased risk of develo** cancer despite successful antiretroviral therapy (ART) …
are at increased risk of develo** cancer despite successful antiretroviral therapy (ART) …
Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy
Exosomes are nanovesicles released from most cell types including immune cells. Prior
studies suggest exosomes play a role in HIV pathogenesis, but little is known about …
studies suggest exosomes play a role in HIV pathogenesis, but little is known about …
Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection
C Tincati, DC Douek, G Marchetti - AIDS research and therapy, 2016 - Springer
Over the past 10 years, extensive work has been carried out in the field of microbial
translocation in HIV infection, ranging from studies on its clinical significance to …
translocation in HIV infection, ranging from studies on its clinical significance to …
Mechanisms of CD8+ T cell‐mediated suppression of HIV/SIV replication
JB McBrien, NA Kumar… - European journal of …, 2018 - Wiley Online Library
In this article, we summarize the role of CD8+ T cells during natural and antiretroviral
therapy (ART)‐treated HIV and SIV infections, discuss the mechanisms responsible for their …
therapy (ART)‐treated HIV and SIV infections, discuss the mechanisms responsible for their …
Clinical and public health implications of acute and early HIV detection and treatment: a sco** review
SE Rutstein, J Ananworanich, S Fidler… - African Journal of …, 2017 - journals.lww.com
Methods We conducted a sco** review [28] synthesizing the most recent literature on
clinical and public health implications of widespread AHI detection and treatment. This …
clinical and public health implications of widespread AHI detection and treatment. This …
CD8+ T-Cell Response to HIV Infection in the Era of Antiretroviral Therapy
Although the combined antiretroviral therapy (cART) has decreased the deaths associated
with the immune deficiency acquired syndrome (AIDS), non-AIDS conditions have emerged …
with the immune deficiency acquired syndrome (AIDS), non-AIDS conditions have emerged …