Recent advances in droplet microfluidics for single-cell analysis

Z Jiang, H Shi, X Tang, J Qin - TrAC Trends in Analytical Chemistry, 2023‏ - Elsevier
Single-cell manipulation and analysis is essential for studying many fundamental biological
processes and discovering cellular heterogeneity. Multi-parameter studies of intercellular …

Recent advancements in electroporation technologies: from bench to clinic

SN Campelo, PH Huang, CR Buie… - Annual review of …, 2023‏ - annualreviews.org
Over the past decade, the increased adoption of electroporation-based technologies has led
to an expansion of clinical research initiatives. Electroporation has been utilized in …

Machine learning for metabolic engineering: A review

CE Lawson, JM Martí, T Radivojevic… - Metabolic …, 2021‏ - Elsevier
Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

Droplet digital PCR of viral‎ DNA/RNA, current progress, challenges, and future perspectives

AA Kojabad, M Farzanehpour… - Journal of Medical …, 2021‏ - Wiley Online Library
High‐throughput droplet‐based digital PCR (ddPCR) is a refinement of the conventional
polymerase chain reaction (PCR)‎ methods. In ddPCR, DNA/RNA is encapsulated …

Pollution to products: recycling of 'above ground'carbon by gas fermentation

M Köpke, SD Simpson - Current Opinion in Biotechnology, 2020‏ - Elsevier
Climate crisis and rapid population growth are posing some of the most urgent challenges to
mankind and have intensified the need for the deployment of carbon recycling and carbon …

[HTML][HTML] Mastering complexity: towards bottom-up construction of multifunctional eukaryotic synthetic cells

K Göpfrich, I Platzman, JP Spatz - Trends in biotechnology, 2018‏ - cell.com
With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …

Nanofiber membrane supported lung-on-a-chip microdevice for anti-cancer drug testing

X Yang, K Li, X Zhang, C Liu, B Guo, W Wen, X Gao - Lab on a Chip, 2018‏ - pubs.rsc.org
Organ-on-a-chip technology can simulate the physiological and pathological
microenvironment of tissues and organs in vitro, thus offering the potential of dispensing with …

Microfluidic systems for infectious disease diagnostics

T Lehnert, MAM Gijs - Lab on a Chip, 2024‏ - pubs.rsc.org
Microorganisms, encompassing both uni-and multicellular entities, exhibit remarkable
diversity as omnipresent life forms in nature. They play a pivotal role by supplying essential …

Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine

Z Isiksacan, A D'Alessandro, SM Wolf… - Proceedings of the …, 2023‏ - pnas.org
Transfusion of red blood cells (RBCs) is one of the most valuable and widespread
treatments in modern medicine. Lifesaving RBC transfusions are facilitated by the cold …

The medicinal chemistry in the era of machines and automation: recent advances in continuous flow technology

A Gioiello, A Piccinno, AM Lozza… - Journal of medicinal …, 2020‏ - ACS Publications
Medicinal chemistry plays a fundamental and underlying role in chemical biology,
pharmacology, and medicine to discover safe and efficacious drugs. Small molecule …