Therapeutic deficiencies with monoaminergic antidepressants invites the need to identify
and develop novel rapid-acting antidepressants. Hitherto, ketamine and esketamine are …

The functions of Sertoli cells in spermatogenesis have attracted much more attention
recently. Normal spermatogenesis depends on Sertoli cells, mainly due to their influence on …

The maternal immune response is essential for successful pregnancy, promoting immune
tolerance to the fetus while maintaining innate and adaptive immunity. Uncontrolled …

Background: Obesity is a worldwide pandemic that causes a multitude of co-morbid
conditions. However, there has been slow progress in understanding the basic …

The Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) is a pleiotropic protein
the activities of which include effects on gene expression and cell transformation, growth …

Increasing evidence supports the beneficial effects of polyphenol-rich diets, including the
traditional Mediterranean diet, for the management of cardiovascular disease, obesity and …

The blood‐testis barrier (BTB) in mammals, such as rats, is composed of the tight junction
(TJ), the basal ectoplasmic specialization (basal ES), the basal tubulobulbar complex (basal …

Adoptive cell therapy holds much promise in the treatment of cancer but results in solid
tumors have been modest. The notable exception is tumor-infiltrating lymphocyte (TIL) …

Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine with a proposed role in obesity-
related insulin resistance. This could be mediated by increased lipolysis in adipose tissue …

Idiopathic multicentric Castleman disease (iMCD) is a poorly understood hematologic
disorder involving cytokine-induced polyclonal lymphoproliferation, systemic inflammation …