Susceptibility genes of hyperuricemia and gout
YL Nian, CG You - Hereditas, 2022 - Springer
Gout is a chronic metabolic disease that seriously affects human health. It is also a major
challenge facing the world, which has brought a heavy burden to patients and society …
challenge facing the world, which has brought a heavy burden to patients and society …
Causal relationship from coffee consumption to diseases and mortality: a review of observational and Mendelian randomization studies including cardiometabolic …
AT Nordestgaard - European Journal of Nutrition, 2022 - Springer
Purpose High coffee consumption is associated with low risk of mortality and morbidity, but
the causality remains unclear. This review aims to discuss findings from observational …
the causality remains unclear. This review aims to discuss findings from observational …
Quantum inflation: A general approach to quantum causal compatibility
Causality is a seminal concept in science: Any research discipline, from sociology and
medicine to physics and chemistry, aims at understanding the causes that could explain the …
medicine to physics and chemistry, aims at understanding the causes that could explain the …
Metabolomics and machine learning identify metabolic differences and potential biomarkers for frequent versus infrequent gout flares
M Wang, R Li, H Qi, L Pang, L Cui, Z Liu… - Arthritis & …, 2023 - Wiley Online Library
Objectives To discover differential metabolites and pathways underlying infrequent gout
flares (InGF) and frequent gout flares (FrGF) using metabolomics and establish a predictive …
flares (InGF) and frequent gout flares (FrGF) using metabolomics and establish a predictive …
[HTML][HTML] Association of the ABCG2 rs2231142 variant with the Framingham Cardiovascular Disease Risk score in the Taiwanese population
Background Serum uric acid (SUA) is an important predictor of cardiovascular events and
mortality. The ABCG2 rs2231142 variant (TT genotype) is associated with hyperuricemia …
mortality. The ABCG2 rs2231142 variant (TT genotype) is associated with hyperuricemia …
Comorbidities in gout and hyperuricemia: causality or epiphenomena?
Although observational studies indicate putative causal effects of serum urate on
comorbidities, Mendelian randomization studies suggest that serum urate does not have a …
comorbidities, Mendelian randomization studies suggest that serum urate does not have a …
[HTML][HTML] Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion
Urine biomarkers reflecting kidney function and handling of dietary sodium and potassium
are strongly associated with several common diseases including chronic kidney disease …
are strongly associated with several common diseases including chronic kidney disease …
Association between habitual coffee consumption and multiple disease outcomes: A Mendelian randomisation phenome-wide association study in the UK Biobank
Background Coffee is the most commonly consumed beverage in the world after water,
however the debate as to whether coffee consumption is beneficial or detrimental to health …
however the debate as to whether coffee consumption is beneficial or detrimental to health …
Associations of Diet with Health Outcomes in the UK Biobank: A Systematic Review
The UK Biobank is a cohort study that collects data on diet, lifestyle, biomarkers, and health
to examine diet–disease associations. Based on the UK Biobank, we reviewed 36 studies …
to examine diet–disease associations. Based on the UK Biobank, we reviewed 36 studies …
Coffee consumption reduces gout risk independently of serum uric acid levels: Mendelian randomization analyses across ancestry populations
Y Shirai, A Nakayama, Y Kawamura… - ACR open …, 2022 - Wiley Online Library
Objective The effects of coffee consumption on serum uric acid (SUA) levels and gout risk
are controversial. There have hitherto been no reports based on Mendelian randomization …
are controversial. There have hitherto been no reports based on Mendelian randomization …