Pain regulation by non-neuronal cells and inflammation
Acute pain is protective and a cardinal feature of inflammation. Chronic pain after arthritis,
nerve injury, cancer, and chemotherapy is associated with chronic neuroinflammation, a …
nerve injury, cancer, and chemotherapy is associated with chronic neuroinflammation, a …
Nociceptor sensory neuron–immune interactions in pain and inflammation
Nociceptor sensory neurons protect organisms from danger by eliciting pain and driving
avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly …
avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly …
Astrocytes in chronic pain and itch
Astrocytes are critical for maintaining the homeostasis of the CNS. Increasing evidence
suggests that a number of neurological and neuropsychiatric disorders, including chronic …
suggests that a number of neurological and neuropsychiatric disorders, including chronic …
An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
[HTML][HTML] Central nervous system targets: glial cell mechanisms in chronic pain
Interactions between central glial cells and neurons in the pain circuitry are critical
contributors to the pathogenesis of chronic pain. In the central nervous system (CNS), two …
contributors to the pathogenesis of chronic pain. In the central nervous system (CNS), two …
Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …
consequence of the pathological functioning of the nervous system rather than only a …
The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as potential …
H Zalpoor, A Akbari, A Samei… - Cellular & Molecular …, 2022 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …
Chemokines in chronic pain: cellular and molecular mechanisms and therapeutic potential
Chronic pain resulting from nerve injury, tissue inflammation, and tumor invasion or
treatment, is a major health problem impacting the quality of life and producing a significant …
treatment, is a major health problem impacting the quality of life and producing a significant …
Interleukin-33 promotes serotonin release from enterochromaffin cells for intestinal homeostasis
The gastrointestinal tract is known as the largest endocrine organ that encounters and
integrates various immune stimulations and neuronal responses due to constant …
integrates various immune stimulations and neuronal responses due to constant …
Sex differences in neuroimmune and glial mechanisms of pain
AM Gregus, IS Levine, KA Eddinger, TL Yaksh… - Pain, 2021 - journals.lww.com
Pain is the primary motivation for seeking medical care. Although pain may subside as
inflammation resolves or an injury heals, it is increasingly evident that persistency of the pain …
inflammation resolves or an injury heals, it is increasingly evident that persistency of the pain …