Over a century of scientific inquiry since the discovery of v-SRC but still no final judgement
on SRC function. However, a significant body of work has defined Src family kinases as key …

When platelet numbers are low or when their function is disabled, the risk of bleeding is
high, which on the one hand indicates that in normal life vascular damage is a rather …

Antiplatelet treatment is of fundamental importance in combatting functions/dysfunction of
platelets in the pathogenesis of cardiovascular and inflammatory diseases. Dysfunction of …

Research over the past decade has extended the prevailing view of the mitochondrion to
include functions well beyond the generation of cellular energy. It is now recognized that …

Cortactin fulfills many functions in various cell types. These functions have been considered
to derive from its ability to activate the Actin-related protein 2/3 (Arp2/3) complex, and are …

Endothelial prostacyclin and nitric oxide potently inhibit platelet functions. Prostacyclin and
nitric oxide actions are mediated by platelet adenylyl and guanylyl cyclases, which …

The transition element zinc, which has recently been identified as an intracellular second
messenger, has been implicated in various signaling pathways, including those leading to …

Junctional adhesion molecules (JAM)-A,-B and-C are cell-cell adhesion molecules of the
immunoglobulin superfamily which are expressed by a variety of tissues, both during …

Current Opinion in Hematology Log in or Register Subscribe to journalSubscribe Get new issue
alertsGet alerts Secondary Logo Journal Logo Advanced Search Toggle navigation Subscribe …

Mitochondria import a large number of nuclear-encoded proteins via membrane-bound
transport machineries; however, little is known about regulation of the preprotein …