Multiple roles of dihomo-γ-linolenic acid against proliferation diseases

X Wang, H Lin, Y Gu - Lipids in health and disease, 2012 - Springer
Considerable arguments remain regarding the diverse biological activities of
polyunsaturated fatty acids (PUFA). One of the most interesting but controversial dietary …

Interaction of brain fatty acid-binding protein with the polyunsaturated fatty acid environment as a potential determinant of poor prognosis in malignant glioma

ME Elsherbiny, M Emara, R Godbout - Progress in lipid research, 2013 - Elsevier
Malignant gliomas are the most common adult brain cancers. In spite of aggressive
treatment, recurrence occurs in the great majority of patients and is invariably fatal …

Docosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion

RL Shinde, PV Devarajan - Drug delivery, 2017 - Taylor & Francis
We disclose microemulsions (ME) of curcumin (CUR) with docosahexaenoic acid (DHA)-rich
oil (CUR DHA ME) for targeted delivery to the brain. MEs of CUR (5 mg/mL) with and without …

Short-term docosapentaenoic acid (22: 5n-3) supplementation increases tissue docosapentaenoic acid, DHA and EPA concentrations in rats

G Kaur, DP Begg, D Barr, M Garg… - British journal of …, 2010 - cambridge.org
The metabolic fate of dietary n-3 docosapentaenoic acid (DPA) in mammals is currently
unknown. The aim of the present study was to determine the extent of conversion of dietary …

FABP7 facilitates uptake of docosahexaenoic acid in glioblastoma neural stem-like cells

WS Choi, X Xu, S Goruk, Y Wang, S Patel, M Chow… - Nutrients, 2021 - mdpi.com
Glioblastoma (GBM) is an aggressive tumor with a dismal prognosis. Neural stem-like cells
contribute to GBM's poor prognosis by driving drug resistance and maintaining cellular …

[HTML][HTML] Modulation of plasma and urine metabolome in colorectal cancer survivors consuming rice bran

I Zarei, RC Oppel, EC Borresen, RJ Brown… - … food, nutrition and …, 2019 - ncbi.nlm.nih.gov
Rice bran has bioactive phytochemicals with cancer protective actions that involve
metabolism by the host and the gut microbiome. Globally, colorectal cancer (CRC) is the …

Lipidomic analysis reveals a radiosensitizing role of gamma-linolenic acid in glioma cells

O Antal, M Péter, L Hackler Jr, I Mán, G Szebeni… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Previous studies have demonstrated that gamma-linolenic acid (GLA) is effective against
glioma cells under both in vitro and in vivo conditions. In the present study we determined …

Proteomics of tumor and serum samples from isocitrate dehydrogenase‐wildtype glioblastoma patients: is the detoxification of reactive oxygen species associated with …

A Clavreul, C Guette, H Lasla, A Rousseau… - Molecular …, 2024 - Wiley Online Library
Proteomics has been little used for the identification of novel prognostic and/or therapeutic
markers in isocitrate dehydrogenase (IDH)‐wildtype glioblastoma (GB). In this study, we …

Effect of hypothyroidism on the expression of nuclear receptors and their co-regulators in mammary gland during lactation in the rat

FCV Arboccó, CV Sasso, DL Nasif, MB Hapon… - Molecular and cellular …, 2015 - Elsevier
Thyroid hormones (TH) regulate mammary function. Hypothyroidism (HypoT) has
deleterious effects on lactation, litter growth and survival. We analyzed the effect of chronic 6 …

[PDF][PDF] Triple negative breast cancer: the role of metabolic pathways

SJR Dean, A Rhodes - The Malaysian journal of pathology, 2014 - researchgate.net
The incidence of breast cancer in Malaysia and other Asian countries is on the increase,
reflecting lifestyle changes some of which are known risk factors for the development of …