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NLRP3 inflammasome in cancer and metabolic diseases
The NLRP3 inflammasome is a multimeric cytosolic protein complex that assembles in
response to cellular perturbations. This assembly leads to the activation of caspase-1, which …
response to cellular perturbations. This assembly leads to the activation of caspase-1, which …
Diverging inflammasome signals in tumorigenesis and potential targeting
Inflammasomes are molecular platforms that assemble upon sensing various intracellular
stimuli. Inflammasome assembly leads to activation of caspase 1, thereby promoting the …
stimuli. Inflammasome assembly leads to activation of caspase 1, thereby promoting the …
[HTML][HTML] Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation
A Iljazovic, U Roy, EJC Gálvez, TR Lesker, B Zhao… - Mucosal …, 2021 - Elsevier
Diverse microbial signatures within the intestinal microbiota have been associated with
intestinal and systemic inflammatory diseases, but whether these candidate microbes …
intestinal and systemic inflammatory diseases, but whether these candidate microbes …
Sequence and cultivation study of Muribaculaceae reveals novel species, host preference, and functional potential of this yet undescribed family
Background Bacteria within family S24-7 (phylum Bacteroidetes) are dominant in the mouse
gut microbiota and detected in the intestine of other animals. Because they had not been …
gut microbiota and detected in the intestine of other animals. Because they had not been …