Population risk factors for severe disease and mortality in COVID-19: A global systematic review and meta-analysis

A Booth, AB Reed, S Ponzo, A Yassaee, M Aral… - PloS one, 2021 - journals.plos.org
Aim COVID-19 clinical presentation is heterogeneous, ranging from asymptomatic to severe
cases. While there are a number of early publications relating to risk factors for COVID-19 …

Risk of bias in studies on prediction models developed using supervised machine learning techniques: systematic review

CLA Navarro, JAA Damen, T Takada, SWJ Nijman… - bmj, 2021 - bmj.com
Objective To assess the methodological quality of studies on prediction models developed
using machine learning techniques across all medical specialties. Design Systematic …

Metabolomic profiles predict individual multidisease outcomes

T Buergel, J Steinfeldt, G Ruyoga, M Pietzner… - Nature medicine, 2022 - nature.com
Risk stratification is critical for the early identification of high-risk individuals and disease
prevention. Here we explored the potential of nuclear magnetic resonance (NMR) …

Protocol for development of a reporting guideline (TRIPOD-AI) and risk of bias tool (PROBAST-AI) for diagnostic and prognostic prediction model studies based on …

GS Collins, P Dhiman, CLA Navarro, J Ma, L Hooft… - BMJ open, 2021 - bmjopen.bmj.com
Introduction The Transparent Reporting of a multivariable prediction model of Individual
Prognosis Or Diagnosis (TRIPOD) statement and the Prediction model Risk Of Bias …

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C …

SR Knight, A Ho, R Pius, I Buchan, G Carson… - bmj, 2020 - bmj.com
Objective To develop and validate a pragmatic risk score to predict mortality in patients
admitted to hospital with coronavirus disease 2019 (covid-19). Design Prospective …

External validation of prognostic models: what, why, how, when and where?

CL Ramspek, KJ Jager, FW Dekker… - Clinical Kidney …, 2021 - academic.oup.com
Prognostic models that aim to improve the prediction of clinical events, individualized
treatment and decision-making are increasingly being developed and published. However …

Cross-sectional studies: strengths, weaknesses, and recommendations

X Wang, Z Cheng - Chest, 2020 - Elsevier
Cross-sectional studies are observational studies that analyze data from a population at a
single point in time. They are often used to measure the prevalence of health outcomes …

There is no such thing as a validated prediction model

B Van Calster, EW Steyerberg, L Wynants… - BMC medicine, 2023 - Springer
Background Clinical prediction models should be validated before implementation in clinical
practice. But is favorable performance at internal validation or one external validation …

Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal

L Wynants, B Van Calster, GS Collins, RD Riley… - bmj, 2020 - bmj.com
Objective To review and appraise the validity and usefulness of published and preprint
reports of prediction models for prognosis of patients with covid-19, and for detecting people …

Calibration: the Achilles heel of predictive analytics

B Van Calster, DJ McLernon, M Van Smeden… - BMC medicine, 2019 - Springer
Background The assessment of calibration performance of risk prediction models based on
regression or more flexible machine learning algorithms receives little attention. Main text …