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The changing metabolic landscape of bile acids–keys to metabolism and immune regulation
Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …
maintain gut microbial community composition and mediate inflammation, and they serve as …
Bacillus cereus food intoxication and toxicoinfection
J Jovanovic, VFM Ornelis, A Madder… - … Reviews in Food …, 2021 - Wiley Online Library
Bacillus cereus is one of the leading etiological agents of toxin‐induced foodborne
diseases. Its omnipresence in different environments, spore formation, and its ability to adapt …
diseases. Its omnipresence in different environments, spore formation, and its ability to adapt …
Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: relationship to neuroimaging and CSF biomarkers
Abstract Introduction Bile acids (BAs) are the end products of cholesterol metabolism
produced by human and gut microbiome co-metabolism. Recent evidence suggests gut …
produced by human and gut microbiome co-metabolism. Recent evidence suggests gut …
Mitochondrial metabolic dysfunction and non-alcoholic fatty liver disease: new insights from pathogenic mechanisms to clinically targeted therapy
Y Zheng, S Wang, J Wu, Y Wang - Journal of Translational Medicine, 2023 - Springer
Metabolic dysfunction-associated fatty liver disease (MAFLD) is among the most widespread
metabolic disease globally, and its associated complications including insulin resistance …
metabolic disease globally, and its associated complications including insulin resistance …
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
Resveratrol induces mitochondrial biogenesis and protects against metabolic decline, but
whether SIRT1 mediates these benefits is the subject of debate. To circumvent the …
whether SIRT1 mediates these benefits is the subject of debate. To circumvent the …
[HTML][HTML] Nonalcoholic fatty liver disease (NAFLD). Mitochondria as players and targets of therapies?
A Di Ciaula, S Passarella, H Shanmugam… - International Journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …
Bile-acid-induced cell injury and protection
Several studies have characterized the cellular and molecular mechanisms of hepatocyte
injury caused by the retention of hydrophobic bile acids (BAs) in cholestatic diseases. BAs …
injury caused by the retention of hydrophobic bile acids (BAs) in cholestatic diseases. BAs …
Glyphosate, pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies
A Samsel, S Seneff - Surgical neurology international, 2015 - pmc.ncbi.nlm.nih.gov
Manganese (Mn) is an often overlooked but important nutrient, required in small amounts for
multiple essential functions in the body. A recent study on cows fed genetically modified …
multiple essential functions in the body. A recent study on cows fed genetically modified …
SRT1720 improves survival and healthspan of obese mice
Sirt1 is an NAD+-dependent deacetylase that extends lifespan in lower organisms and
improves metabolism and delays the onset of age-related diseases in mammals. Here we …
improves metabolism and delays the onset of age-related diseases in mammals. Here we …
[PDF][PDF] Human drug‐induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump
MD Aleo, Y Luo, R Swiss, PD Bonin, DM Potter… - …, 2014 - Wiley Online Library
Drug‐induced liver injury (DILI) accounts for 20‐40% of all instances of clinical hepatic
failure and is a common reason for withdrawal of an approved drug or discontinuation of a …
failure and is a common reason for withdrawal of an approved drug or discontinuation of a …