Dynamic DNA nanotechnology: toward functional nanoscale devices
Dynamic DNA nanotechnology involves the creation of nanoscale devices made of DNA
whose primary function arises from their ability to undergo controlled motion or …
whose primary function arises from their ability to undergo controlled motion or …
The i-motif as a molecular target: more than a complementary DNA secondary structure
SL Brown, S Kendrick - Pharmaceuticals, 2021 - mdpi.com
Stretches of cytosine-rich DNA are capable of adopting a dynamic secondary structure, the i-
motif. When within promoter regions, the i-motif has the potential to act as a molecular switch …
motif. When within promoter regions, the i-motif has the potential to act as a molecular switch …
I-motif DNA structures are formed in the nuclei of human cells
Human genome function is underpinned by the primary storage of genetic information in
canonical B-form DNA, with a second layer of DNA structure providing regulatory control. I …
canonical B-form DNA, with a second layer of DNA structure providing regulatory control. I …
Reconfigurable DNA origami nanocapsule for pH-controlled encapsulation and display of cargo
DNA nanotechnology provides a toolbox for creating custom and precise nanostructures
with nanometer-level accuracy. These nano-objects are often static by nature and serve as …
with nanometer-level accuracy. These nano-objects are often static by nature and serve as …
Reconfigurable pH-Responsive DNA Origami Lattices
DNA nanotechnology enables straightforward fabrication of user-defined and nanometer-
precise templates for a cornucopia of different uses. To date, most of these DNA assemblies …
precise templates for a cornucopia of different uses. To date, most of these DNA assemblies …
pH-dependent cap** interactions induce large-scale structural transitions in i-motifs
We study here a DNA oligonucleotide having the ability to form two different i-motif structures
whose relative stability depends on pH and temperature. The major species at neutral pH is …
whose relative stability depends on pH and temperature. The major species at neutral pH is …
Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase
S Takahashi, JA Brazier… - Proceedings of the …, 2017 - National Acad Sciences
Noncanonical DNA structures that stall DNA replication can cause errors in genomic DNA.
Here, we investigated how the noncanonical structures formed by sequences in genes …
Here, we investigated how the noncanonical structures formed by sequences in genes …
4n–1 Is a “Sweet Spot” in DNA i-Motif Folding of 2′-Deoxycytidine Homopolymers
Strands of DNA with four or more contiguous runs of 2′-deoxycytidine (dC) nucleotides
have the potential to adopt i-motif folds, generally under mildly acidic conditions. Analysis of …
have the potential to adopt i-motif folds, generally under mildly acidic conditions. Analysis of …
Potential G-quadruplexes and i-Motifs in the SARS-CoV-2
Quadruplex structures have been identified in a plethora of organisms where they play
important functions in the regulation of molecular processes, and hence have been …
important functions in the regulation of molecular processes, and hence have been …
Antibacterial activity of DNA-stabilized silver nanoclusters tuned by oligonucleotide sequence
Silver nanoclusters (AgNCs) stabilized by DNA are promising materials with tunable
fluorescent properties, which have been employed in a plethora of sensing systems. In this …
fluorescent properties, which have been employed in a plethora of sensing systems. In this …