Dynamic DNA nanotechnology: toward functional nanoscale devices

M DeLuca, Z Shi, CE Castro, G Arya - Nanoscale Horizons, 2020 - pubs.rsc.org
Dynamic DNA nanotechnology involves the creation of nanoscale devices made of DNA
whose primary function arises from their ability to undergo controlled motion or …

The i-motif as a molecular target: more than a complementary DNA secondary structure

SL Brown, S Kendrick - Pharmaceuticals, 2021 - mdpi.com
Stretches of cytosine-rich DNA are capable of adopting a dynamic secondary structure, the i-
motif. When within promoter regions, the i-motif has the potential to act as a molecular switch …

I-motif DNA structures are formed in the nuclei of human cells

M Zeraati, DB Langley, P Schofield, AL Moye… - Nature …, 2018 - nature.com
Human genome function is underpinned by the primary storage of genetic information in
canonical B-form DNA, with a second layer of DNA structure providing regulatory control. I …

Reconfigurable DNA origami nanocapsule for pH-controlled encapsulation and display of cargo

H Ijäs, I Hakaste, B Shen, MA Kostiainen, V Linko - ACS nano, 2019 - ACS Publications
DNA nanotechnology provides a toolbox for creating custom and precise nanostructures
with nanometer-level accuracy. These nano-objects are often static by nature and serve as …

Reconfigurable pH-Responsive DNA Origami Lattices

S Julin, V Linko, MA Kostiainen - ACS nano, 2023 - ACS Publications
DNA nanotechnology enables straightforward fabrication of user-defined and nanometer-
precise templates for a cornucopia of different uses. To date, most of these DNA assemblies …

pH-dependent cap** interactions induce large-scale structural transitions in i-motifs

I Serrano-Chacón, B Mir, L Cupellini… - Journal of the …, 2023 - ACS Publications
We study here a DNA oligonucleotide having the ability to form two different i-motif structures
whose relative stability depends on pH and temperature. The major species at neutral pH is …

Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase

S Takahashi, JA Brazier… - Proceedings of the …, 2017 - National Acad Sciences
Noncanonical DNA structures that stall DNA replication can cause errors in genomic DNA.
Here, we investigated how the noncanonical structures formed by sequences in genes …

4n–1 Is a “Sweet Spot” in DNA i-Motif Folding of 2′-Deoxycytidine Homopolymers

AM Fleming, Y Ding, RA Rogers, J Zhu… - Journal of the …, 2017 - ACS Publications
Strands of DNA with four or more contiguous runs of 2′-deoxycytidine (dC) nucleotides
have the potential to adopt i-motif folds, generally under mildly acidic conditions. Analysis of …

Potential G-quadruplexes and i-Motifs in the SARS-CoV-2

E Belmonte-Reche, I Serrano-Chacon, C Gonzalez… - PLoS …, 2021 - journals.plos.org
Quadruplex structures have been identified in a plethora of organisms where they play
important functions in the regulation of molecular processes, and hence have been …

Antibacterial activity of DNA-stabilized silver nanoclusters tuned by oligonucleotide sequence

S Javani, R Lorca, A Latorre, C Flors… - … applied materials & …, 2016 - ACS Publications
Silver nanoclusters (AgNCs) stabilized by DNA are promising materials with tunable
fluorescent properties, which have been employed in a plethora of sensing systems. In this …