Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Due to advances in methods for site-specific incorporation of unnatural amino acids (UAAs)
into proteins, a large number of UAAs with tailored chemical and/or physical properties have …

The efficient synthesis of chiral macrocycles with highly enantioselective recognition
remains a challenge. We have addressed this issue by synthesizing a pair of chiral …

Photodynamic therapy is an anti‐cancer treatment that requires illumination of
photosensitizers to induce local cell death. Current near‐infrared organic photosensitizers …

The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …

Organic small‐molecule fluorophores, characterized by flexible chemical structure and
adjustable optical performance, have shown tremendous potential in biosensing. However …

The surging development of bioorthogonal chemistry has profoundly transformed chemical
biology over the last two decades. Involving chemical partners that specifically react together …

Protein labeling approaches are important to study proteins in living cells, and genome
editing tools make it possible to tag endogenous proteins to address the concerns …

Over the past few years, amino acids (AA) have emerged as promising biomaterials for the
synthesis of functional polymers. Owing to the diversity of functional groups in amino acids …

The emergence of antimicrobial resistance is a global health concern and calls for the
development of novel antibiotic agents. Antimicrobial peptides seem to be promising …