The decisive early phase of bone regeneration
Bone has a remarkable endogenous regenerative capacity that enables scarless healing
and restoration of its prior mechanical function, even under challenging conditions such as …
and restoration of its prior mechanical function, even under challenging conditions such as …
Biomaterials in tendon and skeletal muscle tissue engineering: current trends and challenges
Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …
Extracellular matrix in calcific aortic valve disease: architecture, dynamic and perspectives
Calcific Aortic Valve Disease (CAVD) is the most common valvular heart disease in
developed countries and in the ageing population. It is strongly correlated to median age …
developed countries and in the ageing population. It is strongly correlated to median age …
Bioinspired heart valve prosthesis made by silicone additive manufacturing
Synthetic implants made by traditional fabrication routes are not patient specific and rarely
match the performance of their biological counterparts. We present an additive …
match the performance of their biological counterparts. We present an additive …
[HTML][HTML] Advanced robotics to address the translational gap in tendon engineering
Tendon disease is a significant and growing burden to healthcare systems. One strategy to
address this challenge is tissue engineering. A widely held view in this field is that …
address this challenge is tissue engineering. A widely held view in this field is that …
Use of cyclic strain bioreactor for the upregulation of key tenocyte gene expression on Poly (glycerol-sebacate)(PGS) sheets
The inadequate donor source and the difficulty of using natural grafts in tendon repair and
regeneration has led researchers to develop biodegradable and biocompatible synthetic …
regeneration has led researchers to develop biodegradable and biocompatible synthetic …
Gentle cyclic straining of human fibroblasts on electrospun scaffolds enhances their regenerative potential
M Vashaghian, CM Diedrich, B Zandieh-Doulabi… - Acta biomaterialia, 2019 - Elsevier
The extracellular matrix of fascia-like tissues is a resilient network of collagenous fibers that
withstand the forces of daily life. When overstretched, the matrix may tear, with serious …
withstand the forces of daily life. When overstretched, the matrix may tear, with serious …
In vivo and in vitro mechanical loading of mouse Achilles tendons and tenocytes—a pilot study
V Fleischhacker, F Klatte-Schulz, S Minkwitz… - International journal of …, 2020 - mdpi.com
Mechanical force is a key factor for the maintenance, adaptation, and function of tendons.
Investigating the impact of mechanical loading in tenocytes and tendons might provide …
Investigating the impact of mechanical loading in tenocytes and tendons might provide …
A microfabricated platform with hydrogel arrays for 3D mechanical stimulation of cells
Cellular microenvironments present cells with multiple stimuli, including not only soluble
biochemical and insoluble matrix cues but also mechanical factors. Biomaterial array …
biochemical and insoluble matrix cues but also mechanical factors. Biomaterial array …
The osteogenic and tenogenic differentiation potential of C3H10T1/2 (mesenchymal stem cell model) cultured on PCL/PLA electrospun scaffolds in the absence of …
T Baudequin, L Gaut, M Mueller, A Huepkes… - Materials, 2017 - mdpi.com
The differentiation potential of mesenchymal stem cells (MSC) has been extensively tested
on electrospun scaffolds. However, this potential is often assessed with lineage-specific …
on electrospun scaffolds. However, this potential is often assessed with lineage-specific …