Fluid–structure interaction modeling in cardiovascular medicine–A systematic review 2017–2019

M Hirschhorn, V Tchantchaleishvili, R Stevens… - Medical engineering & …, 2020 - Elsevier
Finite element analysis (FEA) and computational fluid dynamics (CFD) are generally
insufficient independently to model the physics of the cardiovascular system. Individually …

The evolution of polyurethane heart valve replacements: How chemistry translates to the clinic

M Crago, A Lee, S Farajikhah, F Oveissi… - Materials Today …, 2022 - Elsevier
Current heart valve replacements (HVRs) fail to comprehensively capture the physiological
behavior of native heart valve tissues, allowing the burden of valvular heart disease to …

Recent trends and progress in the immersed boundary method

WX Huang, FB Tian - Proceedings of the Institution of …, 2019 - journals.sagepub.com
The immersed boundary method is a methodology for dealing with boundary conditions at
fluid–fluid and fluid–solid interfaces. The immersed boundary method has been attracting …

Thinner biological tissues induce leaflet flutter in aortic heart valve replacements

EL Johnson, MCH Wu, F Xu… - Proceedings of the …, 2020 - National Acad Sciences
Valvular heart disease has recently become an increasing public health concern due to the
high prevalence of valve degeneration in aging populations. For patients with severely …

Turbulent systolic flow downstream of a bioprosthetic aortic valve: velocity spectra, wall shear stresses, and turbulent dissipation rates

B Becsek, L Pietrasanta, D Obrist - Frontiers in physiology, 2020 - frontiersin.org
Every year, a quarter million patients receive prosthetic heart valves in aortic valve
replacement therapy. Prosthetic heart valves are known to lead to turbulent blood flow. This …

[HTML][HTML] The relation between aortic morphology and transcatheter aortic heart valve thrombosis: Particle tracing and platelet activation in larger aortic roots with and …

KM Bornemann, SE Jahren, D Obrist - Computers in biology and medicine, 2024 - Elsevier
Transcatheter aortic heart valve thrombosis (THVT) affects long-term valve durability,
transvalvular pressure gradient and leaflet mobility. In this study, we conduct high-fidelity …

Reducing flow separation of an inclined plate via travelling waves

AM Akbarzadeh, I Borazjani - Journal of Fluid Mechanics, 2019 - cambridge.org
Many aquatic animals propel themselves by generating backward traveling waves over their
body, which is thought to reattach the flow when the wave speed (increases both the axial …

Models of shear-induced platelet activation and numerical implementation with computational fluid dynamics approaches

D Han, J Zhang, BP Griffith… - Journal of …, 2022 - asmedigitalcollection.asme.org
Shear-induced platelet activation is one of the critical outcomes when blood is exposed to
elevated shear stress. Excessively activated platelets in the circulation can lead to thrombus …

Fluid-structure coupled biotransport processes in aortic valve disease

MS Sadrabadi, M Hedayat, I Borazjani, A Arzani - Journal of Biomechanics, 2021 - Elsevier
Biological transport processes near the aortic valve play a crucial role in calcific aortic valve
disease initiation and bioprosthetic aortic valve thrombosis. Hemodynamics coupled with the …

Comparison of platelet activation through hinge vs bulk flow in bileaflet mechanical heart valves

M Hedayat, I Borazjani - Journal of biomechanics, 2019 - Elsevier
Bileaflet mechanical heart valves (BMHVs) are prone to thromboembolic complications
which are believed to be initiated by platelet activation. Platelets are activated by non …